A nursing student asks the nursing instructor about the mechanism of the bacteriostatic action of tetracycline. Which explanation is correct?
"Tetracycline inhibits protein synthesis."
"Tetracycline blocks RNA synthesis."
"Tetracycline degrades the bacterial cell wall."
"Tetracycline binds to magnesium ions."
The Correct Answer is A
A. "Tetracycline inhibits protein synthesis."
Explanation: Tetracycline antibiotics interfere with bacterial protein synthesis by binding to the bacterial ribosomes. This binding prevents the attachment of transfer RNA (tRNA) to the messenger RNA (mRNA) complex, effectively inhibiting the production of proteins that are crucial for bacterial growth and replication.
B. "Tetracycline blocks RNA synthesis."
Explanation: This statement is incorrect. Tetracycline primarily affects protein synthesis, not RNA synthesis. It doesn't block the creation of RNA molecules in bacteria.
C. "Tetracycline degrades the bacterial cell wall."
Explanation: This statement is incorrect. Tetracycline antibiotics do not target bacterial cell walls. Agents like penicillins and cephalosporins are examples of antibiotics that disrupt bacterial cell walls.
D. "Tetracycline binds to magnesium ions."
Explanation: This statement is incorrect. Tetracycline does bind to certain metal ions, but it's not primarily through magnesium ions. The binding to bacterial ribosomes is a key mechanism of action for tetracyclines.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Cushing's Syndrome: This is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. It is not related to kidney transplant or immunosuppressive therapy.
B. Hypersensitivity Reaction Type I: Also known as an immediate hypersensitivity reaction or an allergy, this type of reaction involves the immune system's exaggerated response to an allergen. Symptoms can range from mild to severe and occur quickly after exposure to the allergen. While allergies can cause various symptoms, they do not specifically represent rejection of a transplanted organ.
C. Chronic Graft Versus Host Rejection: This term is commonly associated with bone marrow or stem cell transplants. It occurs when immune cells from the donated tissue recognize the recipient's body as foreign and attack various organs or tissues. This process typically happens over a more extended period and is not directly related to the scenario described.
D. Acute Host Versus Graft Rejection: This occurs when the recipient's immune system recognizes the transplanted organ as foreign and launches an immune response against it. It can happen shortly after transplantation if the recipient's immune system is not adequately suppressed. In this case, stopping immunosuppressive therapy can trigger acute rejection, leading to the failure of the transplanted organ.
Correct Answer is B
Explanation
A. Antibiotics are prescribed according to culture and sensitivity reports:
When antibiotics are prescribed based on specific tests like cultures and sensitivity reports, it ensures that the right antibiotic is chosen for the specific bacteria causing the infection. This practice helps in targeting the infection more effectively, reducing the risk of antibiotic resistance.
B. Patients stop taking an antibiotic after they feel better:
This scenario is problematic. When patients start feeling better, they might assume the infection is completely gone and stop taking antibiotics before the prescribed course is finished. This premature discontinuation can leave some bacteria alive, which may develop resistance to the antibiotic used. This practice is a significant contributor to antibiotic resistance.
C. Antibiotics are taken with ascorbic acid (vitamin C):
Ascorbic acid (vitamin C) doesn't have a significant impact on antibiotic resistance. It is not a factor contributing to antibiotic resistance.
D. Antibiotics are taken with water or juice:
Whether antibiotics are taken with water or juice doesn’t directly influence antibiotic resistance. Proper hydration is essential to support the body's overall health, but it doesn't impact the development of antibiotic resistance.
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