Which of the following medications is commonly used for afterload reduction in critical care?

Nitroglycerin

Metoprolol

Furosemide

Epinephrine

Answer and Explanation

The Correct Answer is A

A. Nitroglycerin is a vasodilator commonly used to reduce preload and afterload in critical care settings. By dilating blood vessels, nitroglycerin decreases systemic vascular resistance (afterload), which reduces the workload on the heart and improves cardiac output. It is often used to manage conditions such as acute heart failure, hypertensive emergencies, and acute coronary syndromes.

B. Metoprolol is a beta-blocker that primarily acts to reduce heart rate and myocardial contractility. While it can indirectly reduce afterload by lowering blood pressure, its primary mechanism of action is not targeted at afterload reduction. Metoprolol is commonly used in critical care for various indications, including hypertension, myocardial infarction, and heart failure, but it is not primarily used for afterload reduction.

C. Furosemide is a loop diuretic commonly used to manage volume overload and reduce preload in critical care settings. By promoting diuresis, furosemide decreases circulating blood volume, venous return, and preload, which indirectly reduces afterload. However, its primary mechanism of action is not targeted at afterload reduction but rather at reducing volume overload.

D. Epinephrine is a potent sympathomimetic agent that acts on alpha and beta-adrenergic receptors. While it can increase systemic vascular resistance (afterload) at higher doses due to its alpha-adrenergic effects, it is not commonly used for afterload reduction in critical care settings. Epinephrine is primarily used as a vasopressor to increase blood pressure and cardiac output in patients with shock or cardiac arrest.

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Correct Answer is B

Explanation

B Metformin is an oral antidiabetic medication commonly used to treat type 2 diabetes. There is a potential risk of lactic acidosis when metformin is used in conjunction with contrast material, particularly in patients with underlying renal impairment. Contrast-induced nephropathy can exacerbate renal dysfunction, leading to increased levels of metformin and potentially increasing the risk of lactic acidosis. Therefore, metformin use before or after contrast administration should be carefully monitored, and in some cases, temporarily discontinued to reduce the risk of lactic acidosis.

A Atorvastatin is a statin medication commonly used to lower cholesterol levels. It does not have a direct interaction with contrast material used in cardiac catheterization. Therefore, it does not place the client at risk for acute kidney injury related to contrast-induced nephropathy (CIN).

C Carvedilol is a beta-blocker medication used to treat high blood pressure and heart failure. It does not have a direct interaction with contrast material used in cardiac catheterization. Therefore, it does not place the client at risk for acute kidney injury related to contrast-induced nephropathy (CIN).

D Nitroglycerin is a medication commonly used to relieve chest pain (angina) in patients with coronary artery disease. It does not have a direct interaction with contrast material used in cardiac catheterization. Therefore, it does not place the client at risk for acute kidney injury related to contrast- induced nephropathy (CIN).

A. Left ventricular failure B. Fluid overload C. Hypovolemia D. Intracardiac shunt

Correct Answer is C

Explanation

C. Hypovolemia, or low blood volume, can lead to decreased venous return to the heart and reduced filling pressures. Consequently, CVP may decrease in hypovolemic states. Low CVP may indicate inadequate preload and reduced cardiac output, which are characteristic of hypovolemia.

A. Left ventricular failure typically results in elevated filling pressures rather than low CVP. In left ventricular failure, blood backs up into the pulmonary circulation, leading to increased pulmonary venous pressure and potentially elevated pulmonary capillary wedge pressure (PCWP), which is a surrogate marker for left atrial pressure. This elevated pressure is reflected in the CVP as well, resulting in increased CVP rather than low CVP.

B. Fluid overload typically results in elevated filling pressures and increased CVP rather than low CVP. Excess fluid volume increases venous return to the heart, leading to increased pressure within the central veins and elevated CVP.

D. Intracardiac shunts may cause alterations in cardiac pressures, but they typically do not result in consistently low CVP. Depending on the type and severity of the shunt, the direction and magnitude of pressure changes may vary. However, in the absence of other pathophysiological factors, intracardiac shunts are less likely to cause consistently low CVP.

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Which of the following medications is commonly used for afterload reduction in critical care?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is collecting a medication history from a client who is scheduled to have a cardiac catheterization. Which of the following medications taken by the client interacts with contrast material and places the client at risk for acute kidney injury?

Correct Answer is B

Explanation

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Correct Answer is C

Explanation

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