Which of the following is a primary immunodeficiency disorder?
Human immunodeficiency virus (HIV) infection
Common variable immunodeficiency (CVID)
Rheumatoid arthritis
Diabetes mellitus
The Correct Answer is B
Explanation: The correct answer is b. Common variable immunodeficiency (CVID). CVID is an example of a primary immunodeficiency disorder, which is typically caused by genetic mutations affecting the immune system's development and function.
Incorrect choices:
a. Human immunodeficiency virus (HIV) infection is an example of a secondary immunodeficiency disorder, which occurs due to an external factor, such as a viral infection, damaging the immune system.
c. Rheumatoid arthritis is an autoimmune disorder that affects the joints and is not classified as an immunodeficiency disorder.
d. Diabetes mellitus is a metabolic disorder involving insulin production and does not directly affect the immune system's function.
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Correct Answer is C
Explanation
Explanation: The correct answer is c. Severe combined immunodeficiency (SCID). SCID is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system. Individuals with SCID are highly susceptible to infections and may need to live in a protected environment to avoid exposure to pathogens, hence the term "bubble boy disease."
Incorrect choices:
a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function, but it does not affect B cell function.
b. X-linked agammaglobulinemia is a primary immunodeficiency disorder characterized by a lack of mature B cells and an inability to produce antibodies, but it does not affect T cell function.
d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, but it does not affect B cell function.
Correct Answer is B
Explanation
Explanation: The correct answer is b. X-linked agammaglobulinemia. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a genetic mutation that leads to the absence of mature B cells, resulting in an inability to produce antibodies (immunoglobulins). As a result, individuals with this disorder are highly susceptible to infections, especially bacterial infections.
Incorrect choices:
a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function.
c. Severe combined immunodeficiency (SCID) is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system.
d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, weakening the immune system's ability to fight infections.
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