Which type of immunodeficiency disorder is characterized by a defect in T cell function and is often associated with developmental delays, chronic infections, and autoimmune manifestations?
X-linked agammaglobulinemia
DiGeorge syndrome
Wiskott-Aldrich syndrome
Severe combined immunodeficiency (SCID)
The Correct Answer is B
Explanation: The correct answer is b. DiGeorge syndrome. This disorder is caused by a deletion in chromosome 22, resulting in the underdevelopment of the thymus and parathyroid glands. It leads to impaired T cell function and is associated with developmental delays, chronic infections, and autoimmune problems.
Incorrect choices:
a. X-linked agammaglobulinemia is a primary immunodeficiency disorder that primarily affects B cell function, leading to a deficiency of immunoglobulins (antibodies).
c. Wiskott-Aldrich syndrome is an X-linked recessive disorder characterized by a triad of symptoms: eczema, thrombocytopenia (low platelet count), and immunodeficiency.
d. Severe combined immunodeficiency (SCID) is a group of rare disorders characterized by a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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Related Questions
Correct Answer is C
Explanation
Explanation: The correct answer is c. Immunodeficiency disorders can lead to an increased susceptibility to infections. Immunodeficiency disorders are characterized by a weakened or impaired immune system, making individuals more susceptible to infections, both common and opportunistic.
Incorrect choices:
a. Immunodeficiency disorders result from a weakened immune system, not an overactive one. In overactive immune responses, autoimmune disorders may occur.
b. While some immunodeficiency disorders have a genetic basis, not all cases are caused by genetic factors. Some immunodeficiency disorders can be acquired later in life due to infections, medications, or other factors.
d. Immunodeficiency disorders are not typically treated with anti-inflammatory medications. Treatment may involve immunoglobulin replacement therapy, antiviral medications, or stem cell transplantation, depending on the specific disorder and its underlying cause.
Correct Answer is C
Explanation
Explanation: The correct answer is c. Autoimmune diseases are a potential complication of primary immunodeficiency disorders. When the immune system is deficient or dysfunctional, it may fail to distinguish between self and non-self antigens, leading to the development of autoimmune diseases.
Incorrect choices:
a. Hypertension is a condition characterized by high blood pressure and is not directly related to primary immunodeficiency disorders.
b. Chronic fatigue syndrome is a complex disorder with unknown causes and is not directly related to primary immunodeficiency disorders.
d. Diabetes mellitus is a metabolic disorder caused by insufficient insulin production or insulin resistance and is not directly related to primary immunodeficiency disorders.
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