The nurse is reviewing the diagnostic evaluation for a client with suspected immunodeficiency disorder. Which finding would be consistent with a potential diagnosis of severe combined immunodeficiency (SCID)?

Increased levels of circulating B cells

Elevated immunoglobulin M (IgM) levels

Abnormal antibody response to vaccinations

Absence or significantly reduced T cell levels

Answer and Explanation

The Correct Answer is D

Explanation: The correct answer is d. Absence or significantly reduced T cell levels. Severe combined immunodeficiency (SCID) is characterized by a severe deficiency or absence of T cells, which are essential for cell-mediated immunity.

Incorrect choices:

a. Increased levels of circulating B cells are not characteristic of SCID. In SCID, both T and B cell immunity are affected, and the client may have reduced levels of both.

b. Elevated immunoglobulin M (IgM) levels may occur in certain types of immunodeficiency disorders, but it is not a specific finding for SCID.

c. Abnormal antibody response to vaccinations can be observed in various immunodeficiency disorders, but it does not specifically indicate SCID.

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Correct Answer is C

Explanation

Explanation: The correct answer is c. Frequent and severe infections. One of the hallmark features of immunodeficiency disorders is an increased susceptibility to infections. Individuals with immunodeficiencies may experience frequent and severe infections, including bacterial, viral, and fungal infections.

Incorrect choices:

a. Excessive inflammation at the site of infection is not a common clinical manifestation of immunodeficiency disorders. Immunodeficiencies are characterized by a weakened immune response, which may result in a reduced inflammatory response to infections.

b. Hyperactive immune response to allergens is seen in allergies and autoimmune disorders, not immunodeficiency disorders.

d. Immunodeficiency disorders are characterized by a lack or dysfunction of specific immune components, such as B cells or T cells, leading to a decreased production of antibodies, not increased.

A. Selective IgA deficiency B. DiGeorge syndrome C. X-linked agammaglobulinemia D. Severe combined immunodeficiency (SCID)

Correct Answer is C

Explanation

Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.

Incorrect choices:

a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.

b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.

d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.

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The nurse is reviewing the diagnostic evaluation for a client with suspected immunodeficiency disorder. Which finding would be consistent with a potential diagnosis of severe combined immunodeficiency (SCID)?

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Naxlex Comprehensive Predictor Exams

Which of the following is a common clinical manifestation of immunodeficiency disorders?

Correct Answer is C

Explanation

Which type of immunodeficiency disorder is inherited in an X-linked recessive pattern and primarily affects males, leading to the absence of mature B cells and immunoglobulins?

Correct Answer is C

Explanation

Which of the following is a characteristic of primary immunodeficiency disorders?

Which type of immunodeficiency disorder is characterized by a deficiency or absence of B cells and the inability to produce antibodies?

The nurse is caring for a client with an immunodeficiency disorder. Which precaution should the nurse take when caring for the client?

Which type of immunodeficiency disorder is characterized by a lack of T cell function and is often referred to as "bubble boy disease"?

The nurse is reviewing the diagnostic evaluation for a client with suspected immunodeficiency disorder. Which finding would be consistent with a potential diagnosis of severe combined immunodeficiency (SCID)?

Which of the following is a potential complication of primary immunodeficiency disorders?

Which of the following immunodeficiency disorders is characterized by defective T-cell function and is often diagnosed in infancy or early childhood?

The nurse is caring for an infant suspected of having severe combined immunodeficiency (SCID). Which diagnostic test should the nurse anticipate being prescribed for the infant?