Which of the following drugs inhibit bacterial beta-lactamase?
goldenseal
ceftriaxone (Rocephin)
penicillin
Zosyn (piperacillin/tazobactam)
The Correct Answer is D
A.Goldenseal:
Goldenseal is a plant commonly used in herbal medicine, but it is not a drug that specifically inhibits bacterial beta-lactamase. While goldenseal may have antimicrobial properties, it is not typically used as a beta-lactamase inhibitor in the treatment of bacterial infections.
B. Ceftriaxone (Rocephin):
Ceftriaxone is a third-generation cephalosporin antibiotic. While it is an effective antibiotic for treating a wide range of bacterial infections, it does not have beta-lactamase inhibitor properties. Instead, ceftriaxone is susceptible to degradation by beta-lactamase enzymes produced by certain bacteria.
C. Penicillin:
Penicillin is one of the earliest discovered and most widely used beta-lactam antibiotics. However, many bacteria have developed resistance to penicillin by producing beta-lactamase enzymes. Penicillin itself does not inhibit beta-lactamase; instead, it is often combined with beta-lactamase inhibitors to enhance its effectiveness against beta-lactamase-producing bacteria.
D. Zosyn (piperacillin/tazobactam):
Zosyn is a combination antibiotic containing piperacillin, a broad-spectrum penicillin antibiotic, and tazobactam, a beta-lactamase inhibitor. Tazobactam inhibits the action of beta-lactamase enzymes produced by bacteria, allowing piperacillin to exert its antibacterial effects without being degraded by beta-lactamase. Therefore, Zosyn is the correct answer as it contains a drug that inhibits bacterial beta-lactamase.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Never take with prescription medications:
This statement is not accurate. Many herbal products can interact with prescription medications, potentially leading to adverse effects or reduced efficacy. However, avoiding taking herbal products with prescription medications altogether may not be practical or necessary in all cases. Instead, it's essential to assess for potential interactions and consult with healthcare professionals.
B. Use only one herbal preparation at a time:
This is the correct approach. Using only one herbal preparation at a time allows for better identification of any allergic reactions or adverse effects. If multiple herbal products are taken simultaneously, it can be challenging to determine which product is causing a particular reaction. Starting with one product also simplifies monitoring for efficacy and safety.
C. Take less than the recommended dose initially:
While starting with a lower dose initially may be a prudent approach for some individuals, it is not necessarily the best way to identify allergic or adverse reactions. Taking less than the recommended dose may not provide a full assessment of the product's effects and may not adequately identify potential adverse reactions.
D. Check with a reputable pharmacist:
Consulting with a reputable pharmacist is essential for obtaining information about herbal products, including potential interactions, side effects, and recommended dosages. While a pharmacist can provide valuable guidance, they may not be present during the initial use of the herbal product to monitor for adverse reactions directly.
Correct Answer is B
Explanation
A. Kanamycin (Kantrex):
Kanamycin is an aminoglycoside antibiotic, but it is not commonly used as a first-line treatment for MRSA infections. Aminoglycosides are not typically preferred for treating MRSA because they are not as effective against these resistant bacteria compared to other agents like vancomycin.
B. Vancomycin:
Vancomycin is a glycopeptide antibiotic and is considered the drug of choice for the treatment of MRSA infections, including serious bloodstream infections, pneumonia, and skin and soft tissue infections. It works by inhibiting cell wall synthesis in bacteria, including MRSA.
C. Streptomycin:
Streptomycin is another aminoglycoside antibiotic, similar to kanamycin. Like kanamycin, streptomycin is not typically used as a first-line treatment for MRSA infections because it is less effective against resistant strains compared to other agents like vancomycin.
D. Penicillin:
Penicillin and other beta-lactam antibiotics are ineffective against MRSA because MRSA is resistant to these antibiotics, including methicillin. Therefore, penicillin would not be an appropriate choice for treating MRSA infections.
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