Which of the following drugs inhibit bacterial beta-lactamase?

goldenseal

ceftriaxone (Rocephin)

penicillin

Zosyn (piperacillin/tazobactam)

Answer and Explanation

The Correct Answer is D

A.Goldenseal:

Goldenseal is a plant commonly used in herbal medicine, but it is not a drug that specifically inhibits bacterial beta-lactamase. While goldenseal may have antimicrobial properties, it is not typically used as a beta-lactamase inhibitor in the treatment of bacterial infections.

B. Ceftriaxone (Rocephin):

Ceftriaxone is a third-generation cephalosporin antibiotic. While it is an effective antibiotic for treating a wide range of bacterial infections, it does not have beta-lactamase inhibitor properties. Instead, ceftriaxone is susceptible to degradation by beta-lactamase enzymes produced by certain bacteria.

C. Penicillin:

Penicillin is one of the earliest discovered and most widely used beta-lactam antibiotics. However, many bacteria have developed resistance to penicillin by producing beta-lactamase enzymes. Penicillin itself does not inhibit beta-lactamase; instead, it is often combined with beta-lactamase inhibitors to enhance its effectiveness against beta-lactamase-producing bacteria.

D. Zosyn (piperacillin/tazobactam):

Zosyn is a combination antibiotic containing piperacillin, a broad-spectrum penicillin antibiotic, and tazobactam, a beta-lactamase inhibitor. Tazobactam inhibits the action of beta-lactamase enzymes produced by bacteria, allowing piperacillin to exert its antibacterial effects without being degraded by beta-lactamase. Therefore, Zosyn is the correct answer as it contains a drug that inhibits bacterial beta-lactamase.

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Correct Answer is D

Explanation

A. “I cannot smoke while taking this medication."

This statement is not directly related to the proper use of clarithromycin (Biaxin). While smoking cessation is generally encouraged for overall health, it is not specifically required while taking clarithromycin. However, smoking may affect the effectiveness of antibiotics in general due to its impact on the respiratory system and immune function.

B. “I can quit taking this medication when I feel better."

This statement is incorrect. It is important to emphasize to the client that they should complete the full course of antibiotics as prescribed by their healthcare provider, even if they start to feel better before finishing the medication. Stopping the medication prematurely can lead to incomplete treatment and potentially contribute to antibiotic resistance.

C. “I cannot drive while taking this medication.”

This statement is not accurate. Clarithromycin (Biaxin) is not typically associated with sedation or impairment of driving ability. While some medications may cause drowsiness or other side effects that affect driving, this is not a common side effect of clarithromycin.

D. “I need to take this medication until it is gone."

This statement indicates an understanding of the importance of completing the full course of antibiotics as prescribed by the healthcare provider. Taking the medication until it is finished helps ensure that all bacteria are effectively treated and reduces the risk of antibiotic resistance.

A. penicillin will be effective in treating the infection B. penicillin will not be effective in treating the infection C. the test must be repeated to obtain accurate results D. Ms. Robertson is allergic to penicillin

Correct Answer is A

Explanation

A. Penicillin will be effective in treating the infection:

This interpretation is correct. When the culture and sensitivity test results show that the bacteria causing the infection are sensitive to penicillin, it means that penicillin will effectively inhibit the growth of these bacteria, leading to the resolution of the infection. This sensitivity indicates that penicillin is an appropriate and effective choice for treating the infection.

B. Penicillin will not be effective in treating the infection:

This interpretation is incorrect. If the bacteria are sensitive to penicillin, it means that penicillin will be effective in treating the infection. Sensitivity to penicillin indicates that the bacteria are susceptible to the antimicrobial activity of penicillin, and therefore, penicillin is expected to be effective in eradicating the infection.

C. The test must be repeated to obtain accurate results:

This interpretation is not warranted based on the information provided. If the culture and sensitivity test results indicate that the bacteria causing the infection are sensitive to penicillin, there is no need to repeat the test for accuracy. Sensitivity testing provides valuable information about the susceptibility of bacteria to specific antibiotics, helping healthcare providers make informed decisions about appropriate treatment.

D. Ms. Robertson is allergic to penicillin:

This interpretation is unrelated to the information provided in the scenario. The culture and sensitivity test results indicate the susceptibility of bacteria to penicillin, not whether the patient has an allergy to penicillin. Allergy testing is a separate diagnostic process used to determine if a patient is allergic to penicillin or other medications. Sensitivity testing does not provide information about the patient's allergy status.

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Which of the following drugs inhibit bacterial beta-lactamase?

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Naxlex Comprehensive Predictor Exams

The nurse is discharging a client to home with a prescription for clarithromycin (Biaxin). The nurse knows that teaching has been effective when the client states:

Correct Answer is D

Explanation

When reviewing Ms. Robertson's culture and sensitivity test results, the nurse learns that the bacteria causing Ms. Robertson's infection are sensitive to penicillin. The nurse interprets this result to mean:

Correct Answer is A

Explanation

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