Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?
Penicillins
Fluoroquinolones
Aminoglycosides
Sulfonamides
The Correct Answer is B
A. Penicillins:
Penicillins are a class of antibiotics commonly used to treat various bacterial infections. While they are generally well-tolerated and have a low incidence of adverse effects, they are not typically associated with cartilage toxicity or tendon rupture, including the Achilles tendon.
B. Fluoroquinolones:
Fluoroquinolones are broad-spectrum antibiotics known for their effectiveness against a wide range of bacteria. However, they are associated with several significant adverse effects, including cartilage toxicity and tendon rupture. These adverse effects, particularly tendon rupture, are most commonly observed in weight-bearing tendons such as the Achilles tendon. Fluoroquinolones should be used cautiously, especially in populations at higher risk for tendon injuries.
C. Aminoglycosides:
Aminoglycosides are another class of antibiotics used to treat severe bacterial infections. While they have their own set of potential adverse effects, such as nephrotoxicity and ototoxicity, they are not associated with cartilage toxicity or tendon rupture.
D. Sulfonamides:
Sulfonamides are antibiotics that inhibit bacterial growth by interfering with the synthesis of folate. While they can cause various adverse effects, including skin reactions and hematologic abnormalities, they are not associated with cartilage toxicity or tendon rupture.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Echinacea:
Echinacea is commonly used to support the immune system and may be used to prevent or reduce the severity of colds and other infections. However, it is not typically used specifically for treating menopause-related hot flashes.
B. Saw palmetto:
Saw palmetto is primarily used for managing symptoms related to the prostate gland, such as benign prostatic hyperplasia (BPH), and is not commonly used for treating menopause-related hot flashes in women.
C. Black cohosh:
Black cohosh is one of the most widely studied herbal remedies for managing menopause-related symptoms, including hot flashes. Research suggests that black cohosh may help reduce the frequency and severity of hot flashes in some women experiencing menopausal symptoms.
D. Cranberry juice:
Cranberry juice is often used to promote urinary tract health and prevent urinary tract infections (UTIs). While it may have some health benefits, cranberry juice is not typically used for managing menopause-related hot flashes.
Correct Answer is C
Explanation
A. "Expect your urine to turn pink or red while taking this medication."
This statement is incorrect. Vancomycin does not typically cause urine discoloration. However, red man syndrome, characterized by flushing of the skin, particularly on the face and upper body, can occur with rapid infusion of vancomycin. This is not related to urine color change.
B. "Discontinue the medication once your symptoms subside."
This statement is incorrect. It's crucial for the client to complete the full course of antibiotics as prescribed, even if symptoms improve before completing the treatment course. Discontinuing the medication prematurely can lead to the development of antibiotic resistance and recurrence of the infection.
C. "Notify your provider if you experience any changes in your hearing."
This statement is correct. Vancomycin can potentially cause ototoxicity, which may manifest as changes in hearing, including ringing in the ears (tinnitus) or hearing loss. Clients should be instructed to report any such symptoms to their healthcare provider promptly.
D. "Decrease your fluid intake to 1000ml per day."
This statement is incorrect. Adequate hydration is essential, especially when taking medications like vancomycin, to help prevent kidney damage and promote drug elimination. Restricting fluid intake is not advisable unless specifically instructed by the healthcare provider for a particular medical reason.
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