Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?

A. Prayer:

Prayer is a spiritual practice that involves communicating with a higher power or deity. It has been used for centuries across various cultures and religions as a means of seeking guidance, comfort, and healing. While the direct physical effects of prayer on the body may not be well understood, many people find that prayer can provide emotional support, reduce stress, and promote a sense of well-being. Additionally, some research suggests that prayer may have positive effects on mental health and overall quality of life.

B. Meditation:

Meditation is a practice that involves focusing the mind and cultivating awareness, often through techniques such as mindfulness, breathing exercises, or guided imagery. It has been practiced for centuries in Eastern traditions such as Buddhism and Hinduism, as well as in other cultures around the world. Meditation is known for its ability to promote relaxation, reduce stress, and improve mental clarity. It has also been associated with numerous physical health benefits, including lower blood pressure, improved immune function, and better sleep.

C. Ointments with a steroid base:

Ointments with a steroid base are not typically considered CAM therapies. Instead, they are a form of conventional medical treatment commonly used to reduce inflammation and treat various skin conditions. These ointments contain corticosteroids, which are synthetic drugs that mimic the effects of hormones produced by the adrenal glands. They work by suppressing the body's immune response and reducing inflammation in the affected area. While steroid-based ointments can be effective for treating certain skin conditions, they are not part of traditional CAM practices.

D. Massage:

Massage therapy involves manipulating the body's soft tissues, including muscles, tendons, and ligaments, to promote relaxation, relieve muscle tension, and improve circulation. It has been practiced for centuries in cultures around the world and is commonly used to alleviate stress, reduce pain, and enhance overall well-being. Massage therapy encompasses various techniques, such as Swedish massage, deep tissue massage, and aromatherapy massage, each with its own benefits and applications. Research has shown that massage therapy can have numerous physical and mental health benefits, including reduced anxiety, improved mood, and enhanced immune function.

A.Goldenseal:

Goldenseal is a plant commonly used in herbal medicine, but it is not a drug that specifically inhibits bacterial beta-lactamase. While goldenseal may have antimicrobial properties, it is not typically used as a beta-lactamase inhibitor in the treatment of bacterial infections.

B. Ceftriaxone (Rocephin):

Ceftriaxone is a third-generation cephalosporin antibiotic. While it is an effective antibiotic for treating a wide range of bacterial infections, it does not have beta-lactamase inhibitor properties. Instead, ceftriaxone is susceptible to degradation by beta-lactamase enzymes produced by certain bacteria.

C. Penicillin:

Penicillin is one of the earliest discovered and most widely used beta-lactam antibiotics. However, many bacteria have developed resistance to penicillin by producing beta-lactamase enzymes. Penicillin itself does not inhibit beta-lactamase; instead, it is often combined with beta-lactamase inhibitors to enhance its effectiveness against beta-lactamase-producing bacteria.

D. Zosyn (piperacillin/tazobactam):

Zosyn is a combination antibiotic containing piperacillin, a broad-spectrum penicillin antibiotic, and tazobactam, a beta-lactamase inhibitor. Tazobactam inhibits the action of beta-lactamase enzymes produced by bacteria, allowing piperacillin to exert its antibacterial effects without being degraded by beta-lactamase. Therefore, Zosyn is the correct answer as it contains a drug that inhibits bacterial beta-lactamase.