Before starting antimicrobial therapy, the nurse assesses a patient for possible drug allergy. Which of the following complaints should alert the nurse to a drug allergy?
Headaches
Hives or shortness of breath
Diarrhea
Nausea
The Correct Answer is B
A. Headaches:
Headaches are a common symptom that can occur for various reasons, including stress, tension, dehydration, or as a side effect of medications. While headaches can sometimes occur as a side effect of certain drugs, they are not specific indicators of a drug allergy. Allergic reactions to medications typically involve other symptoms such as rash, hives, itching, swelling, or respiratory symptoms.
B. Hives or shortness of breath:
Hives (urticaria) are raised, red, itchy welts on the skin that can occur as an allergic reaction to medications. They are a common manifestation of drug allergies. Shortness of breath (dyspnea) can occur as part of a severe allergic reaction known as anaphylaxis. Anaphylaxis is a life-threatening allergic reaction characterized by a rapid onset of symptoms, including difficulty breathing, swelling of the throat or tongue, rapid heart rate, and low blood pressure. Both hives and shortness of breath are significant signs of a potential drug allergy and require immediate attention.
C. Diarrhea:
Diarrhea can occur as a side effect of medications, including antibiotics. However, it is not typically a specific indicator of a drug allergy. Diarrhea is more commonly associated with gastrointestinal disturbances or as a reaction to changes in gut flora due to antibiotic use.
D. Nausea:
Nausea is a common side effect of many medications, including antibiotics. While it can be bothersome, nausea alone is not a specific indicator of a drug allergy. Allergic reactions to medications typically involve other symptoms such as rash, hives, itching, swelling, or respiratory symptoms.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Not affected:
This choice suggests that taking ciprofloxacin with antacids does not alter its absorption. However, this is not correct. When ciprofloxacin is taken with antacids containing certain ions (such as aluminum, magnesium, or calcium), the absorption of ciprofloxacin can indeed be affected due to the formation of insoluble complexes, leading to decreased absorption.
B. Delayed:
This choice implies that taking ciprofloxacin with antacids delays its absorption. While it's true that the interaction between ciprofloxacin and certain antacids can alter absorption, the main effect is not typically a delay in absorption but rather a decrease due to the formation of insoluble complexes. Therefore, while "delayed" may somewhat describe the effect, it doesn't fully capture the nature of the interaction.
C. Increased:
This choice suggests that taking ciprofloxacin with antacids increases its absorption. However, this is not accurate. Antacids containing aluminum, magnesium, or calcium can interfere with the absorption of ciprofloxacin by forming insoluble complexes with the drug, leading to decreased absorption rather than an increase.
D. Decreased:
This choice correctly identifies the effect of taking ciprofloxacin with antacids. When ciprofloxacin is taken concurrently with antacids containing aluminum, magnesium, or calcium, the absorption of ciprofloxacin is decreased. The ions in the antacids bind with ciprofloxacin in the gastrointestinal tract, forming insoluble complexes that are poorly absorbed, thereby reducing the effectiveness of the antibiotic.
Correct Answer is A
Explanation
A. Immunocompromised patients:
Immunocompromised patients, whose immune systems are weakened or impaired, are indeed more vulnerable to drug toxicity. This vulnerability can be due to factors such as decreased ability to metabolize and eliminate drugs, increased susceptibility to infections and opportunistic pathogens, and impaired organ function, particularly in the liver and kidneys, which are involved in drug metabolism and excretion.
B. Immunocompetent patients:
Immunocompetent patients have normal immune function and are generally less vulnerable to drug toxicity compared to immunocompromised individuals. However, susceptibility to drug toxicity can still vary depending on factors such as age, underlying health conditions, renal and hepatic function, and concurrent use of other medications.
C. Infants and elderly patients:
Infants and elderly patients are more vulnerable to drug toxicity due to factors such as immature or declining organ function, altered drug metabolism and elimination, and differences in body composition. In infants, organ systems are still developing, while in elderly patients, age-related changes can affect drug pharmacokinetics and increase the risk of adverse reactions.
D. Patients who have allergic reactions:
Patients who have allergic reactions may experience adverse drug reactions if they are exposed to the offending medication again. However, this does not necessarily make them more vulnerable to drug toxicity in general. Allergic reactions are specific immune responses and differ from drug toxicity, which can occur due to various mechanisms unrelated to allergies.
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