The term "virulence" refers to:

substance that can inhibit the growth of bacteria

permanent, inheritable changes to DNA

when a microbe is no longer affected by a drug following treatment with anti-infectives

the severity of disease that an organism is able to cause

Answer and Explanation

The Correct Answer is D

A. Substance that can inhibit the growth of bacteria:

This definition is incorrect. The term "virulence" does not refer to a substance that inhibits bacterial growth. Instead, it pertains to the ability of a microorganism to cause disease.

B. Permanent, inheritable changes to DNA:

This definition is incorrect. Permanent, inheritable changes to DNA are typically referred to as mutations. While mutations can impact the characteristics of microorganisms, the term "virulence" specifically relates to disease-causing ability rather than genetic changes.

C. When a microbe is no longer affected by a drug following treatment with anti-infectives:

This definition is incorrect. The phenomenon described here is known as drug resistance or antimicrobial resistance. It refers to the ability of microorganisms to survive and multiply in the presence of antimicrobial agents, rendering the drugs ineffective.

D. The severity of disease that an organism is able to cause:

This definition is correct. Virulence refers to the degree or severity of disease that an organism, such as a bacterium or virus, is capable of causing. Microorganisms with high virulence can cause severe illness or death in infected hosts, while those with low virulence may cause milder symptoms or no symptoms at all.

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Correct Answer is A

Explanation

A. Immunocompromised patients:

Immunocompromised patients, whose immune systems are weakened or impaired, are indeed more vulnerable to drug toxicity. This vulnerability can be due to factors such as decreased ability to metabolize and eliminate drugs, increased susceptibility to infections and opportunistic pathogens, and impaired organ function, particularly in the liver and kidneys, which are involved in drug metabolism and excretion.

B. Immunocompetent patients:

Immunocompetent patients have normal immune function and are generally less vulnerable to drug toxicity compared to immunocompromised individuals. However, susceptibility to drug toxicity can still vary depending on factors such as age, underlying health conditions, renal and hepatic function, and concurrent use of other medications.

C. Infants and elderly patients:

Infants and elderly patients are more vulnerable to drug toxicity due to factors such as immature or declining organ function, altered drug metabolism and elimination, and differences in body composition. In infants, organ systems are still developing, while in elderly patients, age-related changes can affect drug pharmacokinetics and increase the risk of adverse reactions.

D. Patients who have allergic reactions:

Patients who have allergic reactions may experience adverse drug reactions if they are exposed to the offending medication again. However, this does not necessarily make them more vulnerable to drug toxicity in general. Allergic reactions are specific immune responses and differ from drug toxicity, which can occur due to various mechanisms unrelated to allergies.

Correct Answer is ["125"]

Explanation

To calculate the rate at which the IV pump should be set to deliver 3,000 mL of intravenous fluids over 24 hours, you would divide the total volume (3,000 mL) by the total time (24 hours):

Rate (mL/hr) = Total volume (mL) / Total time (hours)

Rate = 3,000 mL / 24 hours

Rate ≈ 125 mL/hr

Rounding to the nearest whole number, the IV pump should be set to deliver approximately 125 mL/hr.

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The term "virulence" refers to:

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following types of patients are more vulnerable to drug toxicity?

Correct Answer is A

Explanation

A nurse is assisting with care of a client who has a prescription for 3,000 mL of intravenous fluids over the next 24 hr. The nurse should set the IV pump to deliver how many mL/hr? (Round to the nearest whole number)

Correct Answer is ["125"]

Explanation

The nurse explains that is regard to regulation by the Dietary Supplement Health and Education Act, dietary supplements:

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The term "mutations" refers to:

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