The term "virulence" refers to:
substance that can inhibit the growth of bacteria
permanent, inheritable changes to DNA
when a microbe is no longer affected by a drug following treatment with anti-infectives
the severity of disease that an organism is able to cause
The Correct Answer is D
A. Substance that can inhibit the growth of bacteria:
This definition is incorrect. The term "virulence" does not refer to a substance that inhibits bacterial growth. Instead, it pertains to the ability of a microorganism to cause disease.
B. Permanent, inheritable changes to DNA:
This definition is incorrect. Permanent, inheritable changes to DNA are typically referred to as mutations. While mutations can impact the characteristics of microorganisms, the term "virulence" specifically relates to disease-causing ability rather than genetic changes.
C. When a microbe is no longer affected by a drug following treatment with anti-infectives:
This definition is incorrect. The phenomenon described here is known as drug resistance or antimicrobial resistance. It refers to the ability of microorganisms to survive and multiply in the presence of antimicrobial agents, rendering the drugs ineffective.
D. The severity of disease that an organism is able to cause:
This definition is correct. Virulence refers to the degree or severity of disease that an organism, such as a bacterium or virus, is capable of causing. Microorganisms with high virulence can cause severe illness or death in infected hosts, while those with low virulence may cause milder symptoms or no symptoms at all.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. The herbal product must contain only one active ingredient:
This statement is not a legal requirement contained in DSHEA. Many dietary supplements contain multiple active ingredients, such as vitamins, minerals, herbs, amino acids, and other substances. DSHEA does not mandate that dietary supplements contain only one active ingredient.
B. Effectiveness must be demonstrated by the manufacturer:
DSHEA does not require manufacturers to demonstrate the effectiveness of dietary supplements before marketing. Unlike pharmaceutical drugs, which must undergo premarket approval by the Food and Drug Administration (FDA) to demonstrate safety and efficacy, dietary supplements do not need to prove effectiveness to be marketed. Instead, manufacturers are responsible for ensuring the safety of their products and making truthful claims on product labels.
C. Dietary supplements must state that the product is not intended to diagnose, treat, cure, or prevent any disease:
This statement accurately reflects a legal requirement contained in DSHEA. Under DSHEA, dietary supplement labels must include a disclaimer stating that the product is not intended to diagnose, treat, cure, or prevent any disease. This disclaimer helps to clarify that dietary supplements are intended to support general health and well-being rather than to treat specific diseases or medical conditions.
D. Dietary supplements must be tested for safety prior to marketing:
While DSHEA requires manufacturers to ensure the safety of their dietary supplements, it does not mandate standardized premarket testing for safety by regulatory authorities. Instead, manufacturers are responsible for conducting safety assessments and ensuring that their products are safe for consumers. The FDA may take action against manufacturers if a product is found to be unsafe or if it violates regulatory requirements, but premarket testing is not a specific legal requirement under DSHEA.
Correct Answer is B
Explanation
A. Bacteriostatics are narrow spectrum drugs, and bactericidal drugs are broad spectrum:
This statement is incorrect. The spectrum of activity (narrow vs. broad) of an antibiotic refers to the range of bacterial species that it can target, not whether it is bacteriostatic or bactericidal.
B. Bacteriostatic drugs inhibit bacterial growth, and bactericidal drugs actually kill bacteria:
This statement is correct. Bacteriostatic drugs work by inhibiting the growth and reproduction of bacteria without directly killing them, whereas bactericidal drugs directly kill bacteria.
C. Bacteriostatics work by inhibiting protein synthesis, and bactericidal drugs work by inhibiting nucleic acid synthesis:
This statement is incorrect. Both bacteriostatic and bactericidal drugs can target various bacterial cellular processes, including protein synthesis, nucleic acid synthesis, cell wall synthesis, and others. The mechanism of action is not a definitive factor in distinguishing between bacteriostatic and bactericidal drugs.
D. Bacteriostatic drugs actually kill bacteria, and bactericidal drugs inhibit bacterial growth:
This statement is incorrect. It contradicts the established definitions of bacteriostatic and bactericidal drugs. Bacteriostatic drugs inhibit bacterial growth without killing the bacteria, while bactericidal drugs directly kill bacteria.
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