A nurse is reinforcing teaching about vancomycin with a client who has an infection. Which of the following information should the nurse include in the teaching?
"Expect your urine to turn pink or red while taking this medication."
"Discontinue the medication once your symptoms subside.
"Notify your provider if you experience any changes in your hearing."
"Decrease your fluid intake to 1000ml per day."
The Correct Answer is C
A. "Expect your urine to turn pink or red while taking this medication."
This statement is incorrect. Vancomycin does not typically cause urine discoloration. However, red man syndrome, characterized by flushing of the skin, particularly on the face and upper body, can occur with rapid infusion of vancomycin. This is not related to urine color change.
B. "Discontinue the medication once your symptoms subside."
This statement is incorrect. It's crucial for the client to complete the full course of antibiotics as prescribed, even if symptoms improve before completing the treatment course. Discontinuing the medication prematurely can lead to the development of antibiotic resistance and recurrence of the infection.
C. "Notify your provider if you experience any changes in your hearing."
This statement is correct. Vancomycin can potentially cause ototoxicity, which may manifest as changes in hearing, including ringing in the ears (tinnitus) or hearing loss. Clients should be instructed to report any such symptoms to their healthcare provider promptly.
D. "Decrease your fluid intake to 1000ml per day."
This statement is incorrect. Adequate hydration is essential, especially when taking medications like vancomycin, to help prevent kidney damage and promote drug elimination. Restricting fluid intake is not advisable unless specifically instructed by the healthcare provider for a particular medical reason.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Discoloration of body fluids:
Vancomycin can cause discoloration of body fluids, particularly urine, resulting in a brownish discoloration. However, this is not caused by histamine release.
B. Ototoxicity:
Ototoxicity refers to damage to the inner ear structures leading to hearing loss or balance problems. While vancomycin can cause ototoxicity, it is not specifically associated with histamine release.
C. Red-man syndrome
Red-man syndrome, also known as red-neck syndrome or red-person syndrome, is a hypersensitivity reaction characterized by flushing of the skin, particularly the upper body and face, resembling a "red man." This reaction is typically associated with the rapid infusion of vancomycin and is caused by the release of histamine from mast cells and basophils. It is not an allergic reaction but rather a non-immunologic response to vancomycin.
D. Nephrotoxicity:
Nephrotoxicity refers to kidney damage caused by certain medications or toxins. While vancomycin can cause nephrotoxicity, it is not specifically associated with histamine release.

Correct Answer is B
Explanation
A. Kanamycin (Kantrex):
Kanamycin is an aminoglycoside antibiotic, but it is not commonly used as a first-line treatment for MRSA infections. Aminoglycosides are not typically preferred for treating MRSA because they are not as effective against these resistant bacteria compared to other agents like vancomycin.
B. Vancomycin:
Vancomycin is a glycopeptide antibiotic and is considered the drug of choice for the treatment of MRSA infections, including serious bloodstream infections, pneumonia, and skin and soft tissue infections. It works by inhibiting cell wall synthesis in bacteria, including MRSA.
C. Streptomycin:
Streptomycin is another aminoglycoside antibiotic, similar to kanamycin. Like kanamycin, streptomycin is not typically used as a first-line treatment for MRSA infections because it is less effective against resistant strains compared to other agents like vancomycin.
D. Penicillin:
Penicillin and other beta-lactam antibiotics are ineffective against MRSA because MRSA is resistant to these antibiotics, including methicillin. Therefore, penicillin would not be an appropriate choice for treating MRSA infections.
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