A patient at a rehabilitation center is prescribed erythromycin. The nurse is reviewing the patient's medication list, checking to see if there are medications that should not be taken with this antibiotic. One medication is found. What medication should not be taken with erythromycin?
Ibuprofen
Lasix
Lovastatin
Lisinopril
The Correct Answer is C
A. Ibuprofen:
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain and reduce inflammation. There are no significant interactions reported between erythromycin and ibuprofen.
B. Lasix (Furosemide):
Lasix is a diuretic medication used to treat fluid retention (edema) and high blood pressure. There are no significant interactions reported between erythromycin and furosemide.
C. Lovastatin:
Lovastatin is a statin medication used to lower cholesterol levels. Erythromycin can increase the levels of lovastatin in the blood by inhibiting its metabolism through the CYP3A4 enzyme. This can lead to an increased risk of statin-related side effects, including muscle pain and weakness, and in rare cases, rhabdomyolysis.
D. Lisinopril:
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure. There are no significant interactions reported between erythromycin and lisinopril.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["125"]
Explanation
To calculate the rate at which the IV pump should be set to deliver 3,000 mL of intravenous fluids over 24 hours, you would divide the total volume (3,000 mL) by the total time (24 hours):
Rate (mL/hr) = Total volume (mL) / Total time (hours)
Rate = 3,000 mL / 24 hours
Rate ≈ 125 mL/hr
Rounding to the nearest whole number, the IV pump should be set to deliver approximately 125 mL/hr.
Correct Answer is C
Explanation
A. Discoloration of body fluids:
Vancomycin can cause discoloration of body fluids, particularly urine, resulting in a brownish discoloration. However, this is not caused by histamine release.
B. Ototoxicity:
Ototoxicity refers to damage to the inner ear structures leading to hearing loss or balance problems. While vancomycin can cause ototoxicity, it is not specifically associated with histamine release.
C. Red-man syndrome
Red-man syndrome, also known as red-neck syndrome or red-person syndrome, is a hypersensitivity reaction characterized by flushing of the skin, particularly the upper body and face, resembling a "red man." This reaction is typically associated with the rapid infusion of vancomycin and is caused by the release of histamine from mast cells and basophils. It is not an allergic reaction but rather a non-immunologic response to vancomycin.
D. Nephrotoxicity:
Nephrotoxicity refers to kidney damage caused by certain medications or toxins. While vancomycin can cause nephrotoxicity, it is not specifically associated with histamine release.
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