A nurse instructs the patient that if ciprofloxacin (Cipro) is taken with antacids, absorption is
Not affected
delayed
increased
decreased
The Correct Answer is D
A. Not affected:
This choice suggests that taking ciprofloxacin with antacids does not alter its absorption. However, this is not correct. When ciprofloxacin is taken with antacids containing certain ions (such as aluminum, magnesium, or calcium), the absorption of ciprofloxacin can indeed be affected due to the formation of insoluble complexes, leading to decreased absorption.
B. Delayed:
This choice implies that taking ciprofloxacin with antacids delays its absorption. While it's true that the interaction between ciprofloxacin and certain antacids can alter absorption, the main effect is not typically a delay in absorption but rather a decrease due to the formation of insoluble complexes. Therefore, while "delayed" may somewhat describe the effect, it doesn't fully capture the nature of the interaction.
C. Increased:
This choice suggests that taking ciprofloxacin with antacids increases its absorption. However, this is not accurate. Antacids containing aluminum, magnesium, or calcium can interfere with the absorption of ciprofloxacin by forming insoluble complexes with the drug, leading to decreased absorption rather than an increase.
D. Decreased:
This choice correctly identifies the effect of taking ciprofloxacin with antacids. When ciprofloxacin is taken concurrently with antacids containing aluminum, magnesium, or calcium, the absorption of ciprofloxacin is decreased. The ions in the antacids bind with ciprofloxacin in the gastrointestinal tract, forming insoluble complexes that are poorly absorbed, thereby reducing the effectiveness of the antibiotic.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Doxycycline:
Doxycycline is a tetracycline antibiotic that is effective against anthrax. It is commonly used for post-exposure prophylaxis and treatment of anthrax infections.
B. Penicillin:
Penicillin is not typically the first-line antibiotic for treating anthrax. While some strains of Bacillus anthracis may be susceptible to penicillin, other antibiotics like doxycycline or ciprofloxacin are preferred due to their broader spectrum of activity and better penetration into tissues.
C. Oxytetracycline (Terramycin):
Oxytetracycline is another tetracycline antibiotic similar to doxycycline. Like doxycycline, oxytetracycline is effective against anthrax and can be used for post-exposure prophylaxis and treatment of anthrax infections.
D. Ciprofloxacin:
Ciprofloxacin is a fluoroquinolone antibiotic that is effective against anthrax. It is commonly used as an alternative to doxycycline for post-exposure prophylaxis and treatment of anthrax infections, particularly for individuals who cannot tolerate tetracyclines.
Correct Answer is C
Explanation
A. Ibuprofen:
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain and reduce inflammation. There are no significant interactions reported between erythromycin and ibuprofen.
B. Lasix (Furosemide):
Lasix is a diuretic medication used to treat fluid retention (edema) and high blood pressure. There are no significant interactions reported between erythromycin and furosemide.
C. Lovastatin:
Lovastatin is a statin medication used to lower cholesterol levels. Erythromycin can increase the levels of lovastatin in the blood by inhibiting its metabolism through the CYP3A4 enzyme. This can lead to an increased risk of statin-related side effects, including muscle pain and weakness, and in rare cases, rhabdomyolysis.
D. Lisinopril:
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure. There are no significant interactions reported between erythromycin and lisinopril.
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