Which of the following clinical manifestations is often observed in individuals with severe combined immunodeficiency (SCID)?
Recurrent ear infections
Chronic fatigue and lethargy
Failure to thrive
Persistent joint pain
The Correct Answer is C
Explanation: The correct answer is c. Failure to thrive. SCID is a severe form of immunodeficiency that affects multiple components of the immune system, leading to recurrent and severe infections and failure to thrive in affected infants.
Incorrect choices:
a. Recurrent ear infections are more commonly seen in other types of immunodeficiency disorders, such as selective IgA deficiency.
b. Chronic fatigue and lethargy may be seen in various medical conditions but are not specific to SCID.
d. Persistent joint pain is not a characteristic symptom of SCID. It may be associated with other autoimmune or inflammatory conditions.
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Correct Answer is D
Explanation
Explanation: The correct answer is d. Immunoglobulin replacement therapy is a common treatment option for patients with primary immunodeficiency disorders. It involves infusing patients with immunoglobulins (antibodies) to help boost their immune response and protect against infections.
Incorrect choices:
a. Allergy shots are used to desensitize the immune system to specific allergens in individuals with allergies, not to treat primary immunodeficiency disorders.
b. Immunosuppressive medications are used to suppress the immune response in conditions such as autoimmune diseases or after organ transplantation, but they are not typically used to treat primary immunodeficiency disorders.
c. Blood transfusions may be used to treat anemia or certain blood disorders, but they are not a specific treatment for primary immunodeficiency disorders.
Correct Answer is B
Explanation
Explanation: The correct answer is b. Persistent fever and night sweats. Fever and night sweats are common clinical manifestations of immunodeficiency disorders. The immune system's inability to fight off infections can lead to recurrent fevers and night sweats as the body tries to combat pathogens.
Incorrect choices:
a. Hyperactivity and restlessness are not typical clinical manifestations of immunodeficiency disorders. These symptoms are more commonly associated with conditions affecting the central nervous system.
c. Weight gain and increased appetite are not typical clinical manifestations of immunodeficiency disorders. They may be seen in conditions like hypothyroidism or hormonal imbalances.
d. Elevated blood pressure is not a common clinical manifestation of immunodeficiency disorders. It may be seen in conditions like hypertension or cardiovascular disorders.
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