Which of the following clinical manifestations is often observed in individuals with severe combined immunodeficiency (SCID)?

Explanation: The correct answer is c. Primary immunodeficiency disorders are typically present at birth or during early childhood and are caused by genetic defects that affect the function of the immune system. They are not acquired later in life due to environmental factors.

Incorrect choices:

a. Primary immunodeficiency disorders are not acquired later in life; they are usually genetic and present from birth.

b. Primary immunodeficiency disorders are characterized by a weakened or deficient immune response, not an overactive immune response.

d. Primary immunodeficiency disorders are often not easily treatable with antibiotics and antiviral medications because they result from genetic defects in the immune system.

Explanation: The correct answer is d. Maintain strict hand hygiene and utilize protective equipment when providing care. Children with severe combined immunodeficiency (SCID) have a severely compromised immune system, making them highly susceptible to infections. Strict hand hygiene and the use of protective equipment, such as gloves and masks, are essential in preventing the transmission of infections to the child.

Incorrect choices:

a. Placing the child on contact precautions may not be sufficient to protect them from infections due to their high susceptibility. Additional precautions, such as strict hand hygiene and protective equipment, should be implemented.

b. Encouraging the child to play with other children may increase the risk of exposure to infections. Children with SCID should be protected from contact with potential sources of infection.

c. Live attenuated vaccines are contraindicated for children with SCID, as they can cause severe infections. Only inactivated vaccines are recommended to avoid the risk of vaccine-associated infections.