Which of the following clinical manifestations is often observed in individuals with severe combined immunodeficiency (SCID)?
Recurrent ear infections
Chronic fatigue and lethargy
Failure to thrive
Persistent joint pain
The Correct Answer is C
Explanation: The correct answer is c. Failure to thrive. SCID is a severe form of immunodeficiency that affects multiple components of the immune system, leading to recurrent and severe infections and failure to thrive in affected infants.
Incorrect choices:
a. Recurrent ear infections are more commonly seen in other types of immunodeficiency disorders, such as selective IgA deficiency.
b. Chronic fatigue and lethargy may be seen in various medical conditions but are not specific to SCID.
d. Persistent joint pain is not a characteristic symptom of SCID. It may be associated with other autoimmune or inflammatory conditions.
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Related Questions
Correct Answer is B
Explanation
Explanation: The correct answer is b. Primary immunodeficiency disorders result from a genetic or inherited defect, while secondary immunodeficiency disorders are caused by external factors, such as infections or medications.
Incorrect choices:
a. Primary immunodeficiency disorders are present from birth and are usually genetic or inherited, while secondary immunodeficiency disorders can be acquired later in life due to external factors.
c. The manifestations and systems affected by primary and secondary immunodeficiency disorders can vary widely and are not limited to specific areas of the body.
d. Secondary immunodeficiency disorders are more common than primary immunodeficiency disorders, as they can be caused by various factors and are often associated with other medical conditions.
Correct Answer is C
Explanation
Explanation: The correct answer is c. Frequent and severe infections. One of the hallmark features of immunodeficiency disorders is an increased susceptibility to infections. Individuals with immunodeficiencies may experience frequent and severe infections, including bacterial, viral, and fungal infections.
Incorrect choices:
a. Excessive inflammation at the site of infection is not a common clinical manifestation of immunodeficiency disorders. Immunodeficiencies are characterized by a weakened immune response, which may result in a reduced inflammatory response to infections.
b. Hyperactive immune response to allergens is seen in allergies and autoimmune disorders, not immunodeficiency disorders.
d. Immunodeficiency disorders are characterized by a lack or dysfunction of specific immune components, such as B cells or T cells, leading to a decreased production of antibodies, not increased.
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