Which medication is commonly used in the treatment of multiple sclerosis?
Pyridostigmine
Levodopa-carbidopa
Riluzole
Interferon-beta
The Correct Answer is D
A. Pyridostigmine is primarily used in the treatment of myasthenia gravis, a different autoimmune neuromuscular disorder characterized by weakness of voluntary muscles. It works by inhibiting the
enzyme acetylcholinesterase, which increases the levels of acetylcholine at neuromuscular junctions, thereby improving muscle strength. It is not used for treating multiple sclerosis.
B. Levodopa-carbidopa is commonly used to treat Parkinson’s disease. Levodopa is converted to dopamine in the brain, and carbidopa prevents levodopa from being converted into dopamine before it reaches the brain. This combination helps manage the motor symptoms of Parkinson’s disease. It is not used for multiple sclerosis.
C. Riluzole is used primarily for the treatment of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons. It works by reducing the release of glutamate, a neurotransmitter that can be toxic to nerve cells. Riluzole is not used for multiple sclerosis.
D. Interferon-beta is a disease-modifying therapy used in the treatment of multiple sclerosis. It works by modulating the immune system to reduce the frequency and severity of MS relapses. Interferon-beta can help slow the progression of disability and reduce the number of new lesions seen on MRI scans.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. This statement is not accurate in the context of miotic medications. Miotic drugs do not work by blocking neural impulses to the muscles. Instead, they directly affect the eye's pupil size and fluid dynamics. This response does not correctly describe the action of miotic agents.
B. This response is incorrect because miotic medications actually constrict the pupil, not dilate it. In acute angle-closure glaucoma, dilation of the pupil would worsen the condition by further blocking the drainage angle. Miotics are used to constrict the pupil, which helps open the angle between the iris and the cornea, thereby facilitating fluid drainage.
C. Miotic medications cause the pupil to constrict (miosis), which helps in opening the narrow angle between the iris and the cornea. In acute angle-closure glaucoma, the angle is closed or narrow, preventing proper drainage of aqueous humor. By constricting the pupil, miotic medications can help to relieve this obstruction and allow better drainage of fluid, thereby reducing intraocular pressure.
D. This statement is incorrect regarding the action of miotic medications. Miotic drugs do not pull aqueous humor into the bloodstream. Their primary effect is on the pupil's size and the angle of the eye to improve drainage. Medications that reduce aqueous humor production or increase its outflow, such as carbonic anhydrase inhibitors or prostaglandin analogs, are responsible for these actions
Correct Answer is C
Explanation
A. Methylprednisolone is a corticosteroid used to reduce inflammation and suppress the immune system. While corticosteroids are sometimes used in critical care settings, they are not specifically used to prevent stress ulcers. In fact, corticosteroids can increase the risk of gastrointestinal bleeding and may require additional measures to protect the stomach lining.
B. Enoxaparin is a low molecular weight heparin (LMWH) used primarily for the prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). It works as an anticoagulant, preventing blood clots. While enoxaparin is important for preventing thromboembolic events in critically ill patients, it does not specifically address the prevention of stress ulcers.
C. Pantoprazole is a proton pump inhibitor (PPI) that reduces gastric acid production by inhibiting the proton pumps in the stomach lining. PPIs are commonly used to prevent and treat stress ulcers because they help decrease gastric acid secretion, thereby reducing the risk of ulcer formation and bleeding. This makes pantoprazole the appropriate medication to administer to prevent physiologic stress ulcers in a patient with sepsis on a ventilator.
D. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used for pain relief and inflammation. NSAIDs can actually increase the risk of gastrointestinal bleeding and ulceration, especially in critically ill patients.
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