Which factors affect the gastrointestinal absorption of medicines? (Select all that apply.) Select 4 options.
(Select All that Apply.).
Blood flow of the mucous lining of the stomach and intestines.
Drug distribution.
Enzyme activity.
Gastric pH.
Gastric emptying time.
Correct Answer : A,C,D,E
Choice A rationale:
The blood flow of the mucous lining of the stomach and intestines can affect how quickly a drug is absorbed.
Choice B rationale:
Drug distribution refers to how a drug spreads throughout the body, not its absorption in the gastrointestinal tract.
Choice C rationale:
Enzyme activity can affect how a drug is metabolized and absorbed.
Choice D rationale:
Gastric pH can affect drug absorption as some drugs are better absorbed in an acidic environment, while others are better absorbed in an alkaline environment.
Choice E rationale:
Gastric emptying time can affect drug absorption. Drugs may stay in contact with the absorptive tissue longer if the gastric emptying time is slower, allowing for increased absorption.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
The term “Aged” generally refers to individuals who are in the late stages of life, often those over 652. This does not apply to a 40-year-old patient.
Choice B rationale:
“Elderly” is a term often used to refer to individuals who are 65 years of age or older. A 40-year-old patient does not fall into this category.
Choice C rationale:
A 40-year-old patient is considered an “Adult”. According to Erikson’s stages of development, the stage of “generativity vs. stagnation” begins at age 40 and lasts until age 653.
Choice D rationale:
“Older adult” typically refers to individuals who are in their late 60s and beyond. This does not apply to a 40-year-old patient.
Correct Answer is D
Explanation
Choice A rationale:
While it’s true that hydration affects skin absorption, it’s not accurate to say that water-soluble drugs are not readily absorbed because the skin is not fully hydrated.
Choice B rationale:
Inflammation can actually increase the amount of drug absorbed due to increased blood flow and permeability.
Choice C rationale:
Topical administration with percutaneous absorption can be effective in infants, but it’s not always the case.
Choice D rationale:
Infants wearing plastic-coated diapers are indeed more susceptible to skin absorption. This is because the occlusive nature of the diaper can enhance absorption by increasing the hydration of the skin.
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