Which aspect of genetic makeup is most likely to alter a person's response to medication?.
Distribution.
Absorption.
Excretion.
Metabolism.
The Correct Answer is D
Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
Correct Answer is C
Explanation
Choice A rationale:
Giving the medication as ordered despite the patient’s stated allergy could lead to a severe allergic reaction.
Choice B rationale:
While checking the drug insert for information on reactions to the drug is important, the immediate action should be to withhold the medication.
Choice C rationale:
Withholding the medication and notifying the prescriber of the situation is the safest course of action when a patient states they are allergic to the medication.
Choice D rationale:
Giving the medication and monitoring the patient for adverse effects is not safe if the patient has stated they are allergic to the medication.
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