Which aspect of pharmacokinetics should the nurse be most concerned with when caring for a patient with abnormal functioning of hepatic enzymes?.

Choice A rationale:
While a clinical care pathway can guide the treatment plan, it is not specifically designed to develop a detailed plan for a patient in critical condition.
Choice B rationale:
A clinical care pathway is not specifically designed as a communication tool for nurses, but for all healthcare professionals involved in a patient’s care.
Choice C rationale:
A clinical care pathway does not document the plan for admission, but rather the standardized care plan for a specific condition.
Choice D rationale:
A clinical care pathway is indeed a standardized care plan derived from “best practice” patterns.

Choice A rationale:
The blood flow of the mucous lining of the stomach and intestines can affect how quickly a drug is absorbed.
Choice B rationale:
Drug distribution refers to how a drug spreads throughout the body, not its absorption in the gastrointestinal tract.
Choice C rationale:
Enzyme activity can affect how a drug is metabolized and absorbed.
Choice D rationale:
Gastric pH can affect drug absorption as some drugs are better absorbed in an acidic environment, while others are better absorbed in an alkaline environment.
Choice E rationale:
Gastric emptying time can affect drug absorption. Drugs may stay in contact with the absorptive tissue longer if the gastric emptying time is slower, allowing for increased absorption.