Which aspect of pharmacokinetics should the nurse be most concerned with when caring for a patient with abnormal functioning of hepatic enzymes?.
Absorption.
Distribution.
Excretion.
Metabolism.
The Correct Answer is D
Choice A rationale:
Absorption is not primarily affected by the functioning of hepatic enzymes.
Choice B rationale:
Distribution is not the main concern when dealing with abnormal functioning of hepatic enzymes.
Choice C rationale:
Excretion is mainly a function of the kidneys, not the liver.
Choice D rationale:
Metabolism is the aspect of pharmacokinetics most affected by the functioning of hepatic enzymes. The liver plays a crucial role in the metabolism of drugs.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale:
A decrease in blood pressure is a common side effect when a medication increases urine output, as the reduction in fluid volume can lead to lower blood pressure.
Choice B rationale:
While a decrease in blood pressure might be desired in certain conditions (like hypertension), in this context it is a side effect, not the primary desired effect.
Choice C rationale:
The therapeutic effect of the medication in this case is to increase urine output, not to decrease blood pressure.
Correct Answer is ["A","C","D","E"]
Explanation
Choice A rationale:
The blood flow of the mucous lining of the stomach and intestines can affect how quickly a drug is absorbed.
Choice B rationale:
Drug distribution refers to how a drug spreads throughout the body, not its absorption in the gastrointestinal tract.
Choice C rationale:
Enzyme activity can affect how a drug is metabolized and absorbed.
Choice D rationale:
Gastric pH can affect drug absorption as some drugs are better absorbed in an acidic environment, while others are better absorbed in an alkaline environment.
Choice E rationale:
Gastric emptying time can affect drug absorption. Drugs may stay in contact with the absorptive tissue longer if the gastric emptying time is slower, allowing for increased absorption.
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