Which factor associated with aging increases the risk of gastric irritation from nonsteroidal anti-inflammatory drugs (NSAIDS) in older adults?.

Decreased splanchnic blood flow.

Prolonged secretion of gastric acid.

Delayed gastric emptying.

Loss of cells from the gastric plexus.

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Decreased splanchnic blood flow can affect drug absorption and metabolism, but it does not directly increase the risk of gastric irritation from NSAIDs.

Choice B rationale:

Prolonged secretion of gastric acid can contribute to conditions like gastroesophageal reflux disease (GERD), but it is not the primary factor increasing the risk of gastric irritation from NSAIDs in older adults.

Choice C rationale:

Delayed gastric emptying is the correct answer. It allows drugs to stay in contact with the stomach lining for a longer time, which can increase the risk of gastric irritation from NSAIDs.

Choice D rationale:

Loss of cells from the gastric plexus can affect gastric function, but it is not directly linked to an increased risk of gastric irritation from NSAIDs.

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Correct Answer is D

Explanation

Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.

Correct Answer is ["7"]

Explanation

The correct answer is 7 mL. Step 1 is to calculate the concentration of amoxicillin in mg/mL: 250 mg ÷ 5 mL = 50 mg/mL.

Step 2 is to use the calculated concentration to find the volume: Volume (mL) = 350 mg ÷ 50 mg/mL = 7 mL.

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Which factor associated with aging increases the risk of gastric irritation from nonsteroidal anti-inflammatory drugs (NSAIDS) in older adults?.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which aspect of genetic makeup is most likely to alter a person's response to medication?.

Correct Answer is D

Explanation

A nurse is preparing to administer amoxicillin 350 mg PO. Available is amoxicillin 250 mg/5 mL. How many mL should the nurse administer? (Round to the nearest whole number.)

Correct Answer is ["7"]

Explanation

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A nurse is preparing to administer amoxicillin 500 mg PO. Available is amoxicillin 250 mg tablets. How many tablets should the nurse administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)