Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.
Metabolism of drug by the kidneys is slower, so reduced dosage is needed.
Absorption of oral medications is more predictable but more rapid than in adults.
There's an increased risk of toxicity with use of topical agents.
Protein binding of drugs is greater than in adults.
The Correct Answer is C
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
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Related Questions
Correct Answer is A
Explanation
Choice A rationale:
Using a follow-up rinse with a flavored drink is a common practice when administering oral medication to a preschool child. This helps mask the taste of the medication, making it more palatable for the child.
Choice B rationale:
Placing the capsule or tablet under the tongue (sublingual administration) is not typically recommended for preschool children due to the risk of choking.
Choice C rationale:
Supporting the child’s head and holding the child in the lap can be helpful but is not a specific guideline for administering oral medication.
Choice D rationale:
Using chewable tablets can be an option if the child’s teeth are not loose. However, it’s not a general guideline as not all medications come in chewable form.
Correct Answer is D
Explanation
Choice A rationale:
Protein needs do not necessarily accentuate with age. In fact, they may decrease due to reduced physical activity and metabolic rate.
Choice B rationale:
Total fat content does not decrease with age. It’s common for fat distribution to change and increase in certain areas.
Choice C rationale:
Total body water does not increase with age. It usually decreases due to the loss of muscle mass and increase in fat content.
Choice D rationale:
Lean body mass decreases as a person ages. This is a common phenomenon due to changes in cells and tissues.
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