Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.
Metabolism of drug by the kidneys is slower, so reduced dosage is needed.
Absorption of oral medications is more predictable but more rapid than in adults.
There's an increased risk of toxicity with use of topical agents.
Protein binding of drugs is greater than in adults.
The Correct Answer is C
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
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Related Questions
Correct Answer is D
Explanation
Choice A rationale:
While it’s true that hydration affects skin absorption, it’s not accurate to say that water-soluble drugs are not readily absorbed because the skin is not fully hydrated.
Choice B rationale:
Inflammation can actually increase the amount of drug absorbed due to increased blood flow and permeability.
Choice C rationale:
Topical administration with percutaneous absorption can be effective in infants, but it’s not always the case.
Choice D rationale:
Infants wearing plastic-coated diapers are indeed more susceptible to skin absorption. This is because the occlusive nature of the diaper can enhance absorption by increasing the hydration of the skin.
Correct Answer is A
Explanation
Choice A rationale:
The Nursing Minimum Data Set (NMDS) is a classification system that allows for the standardized collection of essential nursing data. This aligns with the terminology in the question.
Choice B rationale:
The term New Medicine Detail Service does not align with the NMDS acronym and does not appear to be a recognized classification system in healthcare.
Choice C rationale:
The term National Medicine Details Set does not align with the NMDS acronym and does not appear to be a recognized classification system in healthcare.
Choice D rationale:
The term Nursing & Medicine Data Service does not align with the NMDS acronym and does not appear to be a recognized classification system in healthcare.
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