Which effect of protein binding on drugs in the bloodstream is accurate?.
Inactivation of the drug.
Increased risk of allergic reaction.
Precipitation of an idiosyncratic reaction.
Accumulation of the drug.
The Correct Answer is D
Choice A rationale:
Protein binding does not inactivate the drug. Instead, it can affect the drug’s distribution and bioavailability.
Choice B rationale:
Protein binding does not directly increase the risk of an allergic reaction. Allergic reactions are typically immune responses to a drug, not a result of protein binding.
Choice C rationale:
An idiosyncratic reaction is an unusual or unexpected reaction to a drug, which is not related to protein binding.
Choice D rationale:
Protein binding can lead to the accumulation of the drug. Drugs often cannot cross membranes mainly due to the high molecular mass of the drug-protein complex, resulting in the accumulation of the active compounds.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Protein needs do not necessarily accentuate with age. In fact, they may decrease due to reduced physical activity and metabolic rate.
Choice B rationale:
Total fat content does not decrease with age. It’s common for fat distribution to change and increase in certain areas.
Choice C rationale:
Total body water does not increase with age. It usually decreases due to the loss of muscle mass and increase in fat content.
Choice D rationale:
Lean body mass decreases as a person ages. This is a common phenomenon due to changes in cells and tissues.
Correct Answer is D
Explanation
Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.
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