Which effect of protein binding on drugs in the bloodstream is accurate?.
Inactivation of the drug.
Increased risk of allergic reaction.
Precipitation of an idiosyncratic reaction.
Accumulation of the drug.
The Correct Answer is D
Choice A rationale:
Protein binding does not inactivate the drug. Instead, it can affect the drug’s distribution and bioavailability.
Choice B rationale:
Protein binding does not directly increase the risk of an allergic reaction. Allergic reactions are typically immune responses to a drug, not a result of protein binding.
Choice C rationale:
An idiosyncratic reaction is an unusual or unexpected reaction to a drug, which is not related to protein binding.
Choice D rationale:
Protein binding can lead to the accumulation of the drug. Drugs often cannot cross membranes mainly due to the high molecular mass of the drug-protein complex, resulting in the accumulation of the active compounds.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
Giving the medication as ordered despite the patient’s stated allergy could lead to a severe allergic reaction.
Choice B rationale:
While checking the drug insert for information on reactions to the drug is important, the immediate action should be to withhold the medication.
Choice C rationale:
Withholding the medication and notifying the prescriber of the situation is the safest course of action when a patient states they are allergic to the medication.
Choice D rationale:
Giving the medication and monitoring the patient for adverse effects is not safe if the patient has stated they are allergic to the medication.
Correct Answer is ["7"]
Explanation
The correct answer is 7 mL. Step 1 is to calculate the concentration of amoxicillin in mg/mL: 250 mg ÷ 5 mL = 50 mg/mL.
Step 2 is to use the calculated concentration to find the volume: Volume (mL) = 350 mg ÷ 50 mg/mL = 7 mL.
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