A patient is taking an antacid concurrently with ketoconazole.
The antacid inhibits the dissolution of ketoconazole.
Which term accurately describes this result?.
Allergic reaction.
Displacement.
Accumulation.
Drug interaction.
The Correct Answer is D
Choice A rationale:
An allergic reaction refers to an immune response to a foreign substance. It does not describe the interaction between an antacid and ketoconazole.
Choice B rationale:
Displacement refers to one drug replacing another at the drug-binding site on proteins, altering the distribution of the displaced drug. It does not describe the interaction between an antacid and ketoconazole.
Choice C rationale:
Accumulation refers to the buildup of a drug in the body due to inadequate metabolism or excretion. It does not describe the interaction between an antacid and ketoconazole.
Choice D rationale:
A drug interaction occurs when the effect of one drug is altered by the administration of another drug. Antacids can slow the dissolution and absorption of ketoconazole, which is a type of drug interaction.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
The fourth phase of the nursing process is planning.
Choice B rationale:
The third phase of the nursing process is diagnosis.
Choice C rationale:
The second phase of the nursing process is diagnosis.
Choice D rationale:
The first phase of the nursing process is assessment.
Correct Answer is ["A","C","D","E"]
Explanation
Choice A rationale:
The blood flow of the mucous lining of the stomach and intestines can affect how quickly a drug is absorbed.
Choice B rationale:
Drug distribution refers to how a drug spreads throughout the body, not its absorption in the gastrointestinal tract.
Choice C rationale:
Enzyme activity can affect how a drug is metabolized and absorbed.
Choice D rationale:
Gastric pH can affect drug absorption as some drugs are better absorbed in an acidic environment, while others are better absorbed in an alkaline environment.
Choice E rationale:
Gastric emptying time can affect drug absorption. Drugs may stay in contact with the absorptive tissue longer if the gastric emptying time is slower, allowing for increased absorption.
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