Which symptom is the most common with a hypersensitivity reaction to a medication?.

Choice A rationale:
A toxic reaction to a drug is best described as a deleterious adverse effect. It is capable of causing injury or death.
Choice B rationale:
An individual’s unexpected effect refers to idiosyncratic reactions, which are unpredictable and vary from person to person.
Choice C rationale:
Physiologic dependence refers to the body’s adaptation to a drug, requiring more of it to achieve a certain effect. It’s not a toxic reaction.
Choice D rationale:
Psychological craving is associated with addiction, not a toxic reaction to a drug.

Choice A rationale:
An increase in the amount of lipid-soluble drugs in the system can occur with decreased albumin and globulin levels, but it does not cause the most concern.
Choice B rationale:
Increased free protein-bound drugs available can lead to an increased potential for adverse drug reactions. This is because these drugs are usually more active and can lead to toxicity.
Choice C rationale:
Water-soluble drugs being absorbed more completely is not typically a concern with decreased albumin and globulin levels.
Choice D rationale:
While metabolism of protein-bound drugs may be decreased, leading to an increased potential for adverse reactions, this is not the primary concern with decreased albumin and globulin levels.