Which potential reaction causes the most concern when administering medication to a patient with decreased albumin and globulin levels?.
There may be an increase in the amount of lipid-soluble drugs in the system.
There may be increased free protein-bound drugs available, increasing the potential for adverse drug reactions.
Water-soluble drugs will be absorbed more completely.
Metabolism of protein-bound drugs will be decreased, increasing the potential for adverse reactions.
The Correct Answer is B
Choice A rationale:
An increase in the amount of lipid-soluble drugs in the system can occur with decreased albumin and globulin levels, but it does not cause the most concern.
Choice B rationale:
Increased free protein-bound drugs available can lead to an increased potential for adverse drug reactions. This is because these drugs are usually more active and can lead to toxicity.
Choice C rationale:
Water-soluble drugs being absorbed more completely is not typically a concern with decreased albumin and globulin levels.
Choice D rationale:
While metabolism of protein-bound drugs may be decreased, leading to an increased potential for adverse reactions, this is not the primary concern with decreased albumin and globulin levels.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.
Correct Answer is ["7"]
Explanation
The correct answer is 7 mL. Step 1 is to calculate the concentration of amoxicillin in mg/mL: 250 mg ÷ 5 mL = 50 mg/mL.
Step 2 is to use the calculated concentration to find the volume: Volume (mL) = 350 mg ÷ 50 mg/mL = 7 mL.
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