A patient takes two medications.
Drug A is taken once per day; drug B is taken every 8 hours.
Which conclusion about drug A is correct?
Has a wider therapeutic range than drug B.
Has a higher rate of protein binding than drug B.
Has a longer half-life than drug B.
Is less toxic than drug B.
The Correct Answer is C
Choice A rationale:
The frequency of drug administration doesn’t necessarily determine the therapeutic range.
Choice B rationale:
Protein binding is not directly related to the frequency of drug administration.
Choice C rationale:
Drug A has a longer half-life than drug B. This is because drugs with longer half-lives need to be administered less frequently.
Choice D rationale:
The toxicity of a drug is not determined by the frequency of its administration.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
An increase in the amount of lipid-soluble drugs in the system can occur with decreased albumin and globulin levels, but it does not cause the most concern.
Choice B rationale:
Increased free protein-bound drugs available can lead to an increased potential for adverse drug reactions. This is because these drugs are usually more active and can lead to toxicity.
Choice C rationale:
Water-soluble drugs being absorbed more completely is not typically a concern with decreased albumin and globulin levels.
Choice D rationale:
While metabolism of protein-bound drugs may be decreased, leading to an increased potential for adverse reactions, this is not the primary concern with decreased albumin and globulin levels.
Correct Answer is D
Explanation
Choice A rationale:
Protein needs do not necessarily accentuate with age. In fact, they may decrease due to reduced physical activity and metabolic rate.
Choice B rationale:
Total fat content does not decrease with age. It’s common for fat distribution to change and increase in certain areas.
Choice C rationale:
Total body water does not increase with age. It usually decreases due to the loss of muscle mass and increase in fat content.
Choice D rationale:
Lean body mass decreases as a person ages. This is a common phenomenon due to changes in cells and tissues.
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