What role do the kidneys have in the pharmacokinetics process?
Excretion
Absorption
Metabolism
Distribution
The Correct Answer is A
A) Excretion:
This is the correct answer. The kidneys play a crucial role in the excretion of drugs and their metabolites from the body. After drugs undergo metabolism in the liver or other tissues, the resulting metabolites are often water-soluble and can be filtered by the kidneys into the urine. This process helps eliminate drugs and their byproducts from the body, preventing their accumulation and potential toxicity.
B) Absorption:
Absorption refers to the movement of drugs from the site of administration into the bloodstream. While the kidneys do not directly facilitate drug absorption, they may indirectly influence drug absorption by regulating blood flow and systemic circulation.
C) Metabolism:
Metabolism, or biotransformation, involves the enzymatic alteration of drugs into metabolites, which are often more water-soluble and easier to excrete. While the liver is the primary site of drug metabolism, the kidneys do not play a direct role in drug metabolism.
D) Distribution:
Distribution refers to the movement of drugs from the bloodstream to various tissues and organs in the body. While the kidneys do not directly influence drug distribution, changes in renal function can affect drug distribution by altering blood flow and plasma protein binding. However, the primary role of the kidneys in pharmacokinetics is excretion, not distribution.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["43.1"]
Explanation
Here's how we can find the dose:
Convert client weight to kilograms (kg):
We know 1 kg = 2.205 pounds.
Client weight (kg) = 95 lbs / 2.205 lb/kg = 43.1 kg (round to one decimal place for accuracy in calculation).
Calculate the enoxaparin dosage per dose:
Prescribed dosage: 1 mg/kg/dose
Client weight (kg): 43.1 kg (rounded value from step 1)
Enoxaparin dose per dose (mg) = Dosage (mg/kg/dose) x Client weight (kg)
Enoxaparin dose per dose (mg) = 1 mg/kg/dose * 43.1 kg = 43.1 mg (round to nearest tenth as requested)
Therefore, the nurse should administer approximately 43.1 mg of enoxaparin per dose.
Correct Answer is D
Explanation
A) Apples:
Apples are not contraindicated with spironolactone use. There are no known interactions between spironolactone and apples.
B) Fish:
Fish is not contraindicated with spironolactone use. There are no known interactions between spironolactone and fish.
C) Crackers:
Crackers are not contraindicated with spironolactone use. There are no known interactions between spironolactone and crackers.
D) Bananas:
Bananas are high in potassium, and spironolactone is a potassium-sparing diuretic. Ingesting potassium-rich foods such as bananas while taking spironolactone can increase the risk of hyperkalemia. Therefore, the nurse should instruct the client to avoid consuming large amounts of potassium-rich foods like bananas to prevent adverse effects."
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