What role do the kidneys have in the pharmacokinetics process?

Excretion

Absorption

Metabolism

Distribution

Answer and Explanation

The Correct Answer is A

A) Excretion:
This is the correct answer. The kidneys play a crucial role in the excretion of drugs and their metabolites from the body. After drugs undergo metabolism in the liver or other tissues, the resulting metabolites are often water-soluble and can be filtered by the kidneys into the urine. This process helps eliminate drugs and their byproducts from the body, preventing their accumulation and potential toxicity.

B) Absorption:
Absorption refers to the movement of drugs from the site of administration into the bloodstream. While the kidneys do not directly facilitate drug absorption, they may indirectly influence drug absorption by regulating blood flow and systemic circulation.

C) Metabolism:
Metabolism, or biotransformation, involves the enzymatic alteration of drugs into metabolites, which are often more water-soluble and easier to excrete. While the liver is the primary site of drug metabolism, the kidneys do not play a direct role in drug metabolism.

D) Distribution:
Distribution refers to the movement of drugs from the bloodstream to various tissues and organs in the body. While the kidneys do not directly influence drug distribution, changes in renal function can affect drug distribution by altering blood flow and plasma protein binding. However, the primary role of the kidneys in pharmacokinetics is excretion, not distribution.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is B

Explanation

A) Bicarbonate:
While bicarbonate levels may be relevant in some cases, they are not typically a primary consideration before administering furosemide. Furosemide primarily affects electrolyte balance, particularly potassium and sodium, rather than bicarbonate levels.

B) Potassium:
This is the correct answer. Before administering furosemide, it is essential to review the client's potassium levels because furosemide is a loop diuretic that can lead to potassium depletion. Monitoring potassium levels helps prevent hypokalemia, which can lead to cardiac dysrhythmias and other complications, especially in clients with heart failure.

C) Phosphate:
Phosphate levels are not typically a primary concern before administering furosemide. Furosemide primarily affects sodium and potassium levels rather than phosphate levels.

D) Carbon dioxide:
Carbon dioxide levels are not typically a primary consideration before administering furosemide. Furosemide primarily affects electrolyte balance rather than carbon dioxide levels.

Correct Answer is ["100"]

Explanation

We are given the following information:

Medication: Ticarcillin/clavulanate 3.1 g

Administration route: Intermittent IV bolus over 30 minutes

Available solution: Ticarcillin/clavulanate 3.1 g in 50 mL 0.9% sodium chloride (NSS)

However, the IV pump controls the rate of delivery over time (usually in hours). An intermittent bolus means the medication is infused all at once over a shorter period (30 minutes in this case).

The pump rate calculation here focuses on the total volume of the available solution containing the medication to be delivered, not necessarily on the medication amount itself.

Therefore, we need to find the rate at which the total volume of 50 mL solution should be delivered over 30 minutes.

Conversion is necessary because pump rates are typically set in hours (hr).

Time (hours) = 30 minutes / 60 minutes/hour = 0.5 hours

Now, calculate the flow rate:

Flow rate (mL/hr) = Total volume (mL) / Infusion time (hours)

Flow rate (mL/hr) = 50 mL / 0.5 hours = 100 mL/hr

Round to the nearest whole number as requested.

Therefore, the nurse should set the pump to deliver approximately 100 mL/hr. This ensures the total 50 mL solution containing the 3.1 g of ticarcillin/clavulanate is delivered over the intended 30-minute period.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

What role do the kidneys have in the pharmacokinetics process?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who has heart failure and a new prescription for furosemide. Which of the following laboratory values should the nurse review before administering furosemide?

Correct Answer is B

Explanation

Correct Answer is ["100"]

Explanation

A nurse is explaining myasthenia gravis to a family. Which of the following points would be included in the explanation? (Select All that Apply.)

A nurse is educating a client about the sympathetic nervous system. Which of the following statements is correct?

A client is teaching a client who has a new prescription for hydrochlorothiazide for management of hypertension. Which of the following Instructions should the nurse include?

A 78-year-old client is admitted to the emergency department with a heart rate of 34 beats/min. Family members tell the nurse that the client may have mistakenly taken several doses of donepezil. The nurse should anticipate what intervention to treat the client's bradycardia?

A resident of a long-term care facility receives 12.5 mg metoprolol (Lopressor) at 8 AM and 8 PM daily. Before administering this drug, the nurse should perform and document what assessment findings?

A nurse is providing teaching to a client who has hypertension and a new prescription for verapamil. Which of the following beverages should the nurse tell the client to avoid while taking this medication?