What role do the kidneys have in the pharmacokinetics process?

Excretion

Absorption

Metabolism

Distribution

Answer and Explanation

The Correct Answer is A

A) Excretion:
This is the correct answer. The kidneys play a crucial role in the excretion of drugs and their metabolites from the body. After drugs undergo metabolism in the liver or other tissues, the resulting metabolites are often water-soluble and can be filtered by the kidneys into the urine. This process helps eliminate drugs and their byproducts from the body, preventing their accumulation and potential toxicity.

B) Absorption:
Absorption refers to the movement of drugs from the site of administration into the bloodstream. While the kidneys do not directly facilitate drug absorption, they may indirectly influence drug absorption by regulating blood flow and systemic circulation.

C) Metabolism:
Metabolism, or biotransformation, involves the enzymatic alteration of drugs into metabolites, which are often more water-soluble and easier to excrete. While the liver is the primary site of drug metabolism, the kidneys do not play a direct role in drug metabolism.

D) Distribution:
Distribution refers to the movement of drugs from the bloodstream to various tissues and organs in the body. While the kidneys do not directly influence drug distribution, changes in renal function can affect drug distribution by altering blood flow and plasma protein binding. However, the primary role of the kidneys in pharmacokinetics is excretion, not distribution.

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Correct Answer is A

Explanation

A) Hypoxemia:
This is the correct answer. Atelectasis, which is the collapse or incomplete inflation of the lung, can lead to impaired gas exchange and subsequent hypoxemia. As lung volume decreases due to collapse, ventilation-perfusion (V/Q) mismatch occurs, resulting in decreased oxygenation of arterial blood. Hypoxemia is a common finding in individuals with atelectasis and may manifest as decreased oxygen saturation levels on pulse oximetry or arterial blood gas analysis.

B) Apnea:
Apnea, defined as the cessation of breathing, is not typically associated with atelectasis. While atelectasis can contribute to respiratory compromise and may result in respiratory distress, including tachypnea or increased work of breathing, it does not usually lead to complete cessation of breathing.

C) Pleural effusion:
A pleural effusion is the accumulation of fluid in the pleural space surrounding the lungs. While pleural effusion may occur concurrently with atelectasis, it is not an expected finding specifically associated with atelectasis itself. Pleural effusion may cause respiratory symptoms such as dyspnea or chest pain but is not a primary manifestation of atelectasis.

D) Dysphagia:
Dysphagia, or difficulty swallowing, is unrelated to atelectasis. While dysphagia can occur as a result of various conditions affecting the esophagus or neurological control of swallowing, it is not a typical manifestation of atelectasis. Atelectasis primarily affects the lungs and respiratory function rather than swallowing function.

A. Temperature and respiratory rate B. Heart rate and blood pressure C. Level of consciousness and pain level D. Oxygen saturation and respiratory rate

Correct Answer is B

Explanation

A) Temperature and respiratory rate:
While monitoring temperature and respiratory rate are important aspects of a comprehensive assessment, they are not the priority assessments before administering metoprolol. Metoprolol is a beta-blocker primarily used to lower heart rate and blood pressure, so assessing the client's heart rate and blood pressure is more relevant.

B) Heart rate and blood pressure:
This is the correct answer. Before administering metoprolol, it is essential to assess the client's heart rate and blood pressure. Metoprolol is a beta-blocker medication that primarily affects heart rate and blood pressure. Monitoring these vital signs helps ensure that the medication is administered safely and effectively.

C) Level of consciousness and pain level:
Assessing the client's level of consciousness and pain level are important aspects of nursing care, but they are not the priority assessments before administering metoprolol. These assessments may be relevant depending on the client's overall condition and specific care needs, but they are not directly related to the action or side effects of metoprolol.

D) Oxygen saturation and respiratory rate:
Monitoring oxygen saturation and respiratory rate are important aspects of respiratory assessment, but they are not the priority assessments before administering metoprolol. While metoprolol can affect respiratory function as a potential side effect, its primary action is on heart rate and blood pressure. Therefore, assessing heart rate and blood pressure are more pertinent before administering this medication.

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What role do the kidneys have in the pharmacokinetics process?

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Naxlex Comprehensive Predictor Exams

A nurse is caring for a client 1 day postoperative who has developed atelectasis. Which of the following manifestations is an expected finding for this condition?

Correct Answer is A

Explanation

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Correct Answer is B

Explanation

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