What role do the kidneys have in the pharmacokinetics process?

Excretion

Absorption

Metabolism

Distribution

Answer and Explanation

The Correct Answer is A

A) Excretion:
This is the correct answer. The kidneys play a crucial role in the excretion of drugs and their metabolites from the body. After drugs undergo metabolism in the liver or other tissues, the resulting metabolites are often water-soluble and can be filtered by the kidneys into the urine. This process helps eliminate drugs and their byproducts from the body, preventing their accumulation and potential toxicity.

B) Absorption:
Absorption refers to the movement of drugs from the site of administration into the bloodstream. While the kidneys do not directly facilitate drug absorption, they may indirectly influence drug absorption by regulating blood flow and systemic circulation.

C) Metabolism:
Metabolism, or biotransformation, involves the enzymatic alteration of drugs into metabolites, which are often more water-soluble and easier to excrete. While the liver is the primary site of drug metabolism, the kidneys do not play a direct role in drug metabolism.

D) Distribution:
Distribution refers to the movement of drugs from the bloodstream to various tissues and organs in the body. While the kidneys do not directly influence drug distribution, changes in renal function can affect drug distribution by altering blood flow and plasma protein binding. However, the primary role of the kidneys in pharmacokinetics is excretion, not distribution.

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Correct Answer is ["43.1"]

Explanation

Here's how we can find the dose:

Convert client weight to kilograms (kg):

We know 1 kg = 2.205 pounds.

Client weight (kg) = 95 lbs / 2.205 lb/kg = 43.1 kg (round to one decimal place for accuracy in calculation).

Calculate the enoxaparin dosage per dose:

Prescribed dosage: 1 mg/kg/dose

Client weight (kg): 43.1 kg (rounded value from step 1)

Enoxaparin dose per dose (mg) = Dosage (mg/kg/dose) x Client weight (kg)

Enoxaparin dose per dose (mg) = 1 mg/kg/dose * 43.1 kg = 43.1 mg (round to nearest tenth as requested)

Therefore, the nurse should administer approximately 43.1 mg of enoxaparin per dose.

A. The client should try to take in all of the required dietary fiber with the morning meal. B. The client should drink two to three 8 oz glasses of water each day. C. The client should follow a high-fiber diet to establish bowel regularity. D. The client should be taught that the goal of therapy is to have a bowel movement daily.

Correct Answer is C

Explanation

A) The client should try to take in all of the required dietary fiber with the morning meal:
While it's beneficial for clients to consume dietary fiber with meals to promote regular bowel movements, focusing solely on the morning meal may not provide adequate fiber intake throughout the day. It's essential for clients with chronic constipation to maintain a consistent intake of dietary fiber with each meal and snack.

B) The client should drink two to three 8 oz glasses of water each day:
Hydration is important for overall bowel health, but simply drinking water may not be sufficient to alleviate chronic constipation. While increasing fluid intake can help soften stools and prevent constipation, the amount of water needed varies among individuals. It's important for clients to drink enough fluids throughout the day to maintain hydration and support gastrointestinal function.

C) The client should follow a high-fiber diet to establish bowel regularity:
This is the correct answer. Increasing dietary fiber intake is a cornerstone of managing chronic constipation. A high-fiber diet can help add bulk to stools, improve bowel motility, and establish regularity. The nurse should educate the client about incorporating fiber-rich foods such as fruits, vegetables, whole grains, and legumes into their daily diet to promote optimal bowel function.

D) The client should be taught that the goal of therapy is to have a bowel movement daily:
While having a daily bowel movement may be a reasonable goal for some individuals, it's not universally applicable to all clients with chronic constipation. Bowel habits vary among individuals, and the frequency of bowel movements needed to establish regularity depends on factors such as diet, activity level, and overall health. The focus of therapy should be on achieving comfortable and regular bowel movements rather than a specific frequency.

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What role do the kidneys have in the pharmacokinetics process?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is ["43.1"]

Explanation

A nurse is preparing a teaching plan for a client who has chronic constipation secondary to irregular bowel habits. Which of the following should the nurse plan to include in the teaching?

Correct Answer is C

Explanation

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