A nurse is explaining myasthenia gravis to a family. Which of the following points would be included in the explanation? (Select All that Apply.)
Is it caused by demyelination of the nerve fibers.
Is it thought to be an autoimmune disease.
It is associated with destruction of acetylcholine receptor sites.
Once symptoms present, it has a 5-year survival rate.
It is a chronic and progressive muscular disease.
Is it best treated with antibiotics.
Correct Answer : B,C,E
A) Is it caused by demyelination of the nerve fibers:
Myasthenia gravis is not primarily caused by demyelination of nerve fibers. It is characterized by dysfunction at the neuromuscular junction, specifically involving the acetylcholine receptors.
B) Is it thought to be an autoimmune disease:
This is correct. Myasthenia gravis is considered an autoimmune disorder in which the body's immune system mistakenly targets and attacks its own tissues, particularly the acetylcholine receptors at the neuromuscular junction.
C) It is associated with destruction of acetylcholine receptor sites:
This is correct. In myasthenia gravis, there is a reduction in the number of functional acetylcholine receptors due to autoimmune-mediated destruction or blocking of these receptors.
D) Once symptoms present, it has a 5-year survival rate:
This statement is inaccurate. Myasthenia gravis is a chronic condition, but survival rates are not determined by the onset of symptoms. With appropriate treatment, many individuals with myasthenia gravis can manage their symptoms effectively and have a normal life expectancy.
E) It is a chronic and progressive muscular disease:
This is correct. Myasthenia gravis is a chronic neuromuscular disorder characterized by fluctuating muscle weakness and fatigue. While it is chronic, it is not necessarily progressive in all cases, as symptoms may stabilize or improve with treatment.
F) Is it best treated with antibiotics:
Antibiotics are not the primary treatment for myasthenia gravis. Treatment typically involves medications that enhance neuromuscular transmission, such as acetylcholinesterase inhibitors or immunosuppressive drugs, along with other supportive measures.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A) Loss of protective respiratory mechanisms due to prolonged irritation or damage:
Individuals with COPD often experience a progressive loss of protective respiratory mechanisms over time. Chronic exposure to irritants such as cigarette smoke leads to inflammation, structural changes in the airways, and destruction of lung tissue, impairing the body's ability to clear mucus, trap foreign particles, and maintain normal lung function. This loss of protective mechanisms contributes to the hallmark symptoms of COPD, including airflow limitation, chronic cough, and increased susceptibility to respiratory infections.
B) Localized swelling and inflammation within the lungs:
While inflammation is a hallmark feature of COPD, it typically manifests as widespread inflammation throughout the lungs rather than localized swelling. In COPD, chronic exposure to irritants leads to a systemic inflammatory response that affects the entire respiratory tract, including the bronchi and alveoli. This inflammation contributes to airway obstruction, mucus hypersecretion, and the development of respiratory symptoms.
C) An acute viral infection of the respiratory tract:
While individuals with COPD are at increased risk of respiratory infections, including viral infections such as influenza and respiratory syncytial virus (RSV), COPD itself is a chronic, progressive respiratory condition characterized by persistent airflow limitation. Acute viral infections may exacerbate COPD symptoms and lead to worsening respiratory function, but they are not inherent features of the disease itself.
D) Inflammation and swelling of the sinus membranes over a prolonged period:
Sinus inflammation and swelling, known as sinusitis, are not typically considered primary features of COPD. While individuals with COPD may experience comorbid conditions such as chronic rhinosinusitis, which can contribute to respiratory symptoms and exacerbations, sinus inflammation is not a defining characteristic of the disease.
Correct Answer is C
Explanation
A) Postoperative patients:
Antitussives may be used postoperatively to alleviate coughing, but they are not necessarily best used in this population. Postoperative patients may have different needs based on their surgical procedure and overall health status.
B) Asthma patients:
Antitussives are generally not recommended for asthma patients because they can suppress the cough reflex, which may be important for clearing mucus and irritants from the airways. Asthma patients often have productive coughs associated with bronchial inflammation and excess mucus production.
C) Patients with a dry, irritating cough:
Antitussives are most effective for patients with a dry, irritating cough, as they help suppress the cough reflex and provide relief from coughing without producing sputum.
D) COPD patients who tire easily:
While antitussives may provide symptomatic relief for some COPD patients with a dry, nonproductive cough, they are not necessarily best used in this population. COPD patients may have varied responses to antitussive therapy, and treatment decisions should be individualized based on their overall condition and symptoms."
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