What are the risk factors associated with peptic ulcer disease?

(Select All that Apply.)

A) Treatment with PPIs to decrease stomach acid:
Proton-pump inhibitors (PPIs) are used to decrease stomach acid production and are commonly prescribed for conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. However, they do not address the underlying cause of pancreatic insufficiency, which is the deficiency of pancreatic enzymes.

B) Treatment with stimulant laxatives:
Stimulant laxatives are used to stimulate bowel movements and are not indicated for the treatment of pancreatic insufficiency. Pancreatic insufficiency primarily affects the digestion of nutrients rather than bowel motility.

C) Replacement therapy with pancreatic enzymes.
Pancreatic insufficiency occurs when the pancreas does not produce enough digestive enzymes to properly digest food, leading to malabsorption of nutrients. Replacement therapy with pancreatic enzymes is the mainstay of treatment for pancreatic insufficiency. These enzymes, often prescribed in the form of pancreatic enzyme replacement therapy (PERT), help to supplement the deficient enzymes and aid in the digestion of fats, proteins, and carbohydrates.

D) Decrease food intake:
Decreasing food intake is not an appropriate treatment for pancreatic insufficiency. In fact, individuals with pancreatic insufficiency may need to increase their food intake to compensate for malabsorption and ensure adequate nutrition. Restricting food intake would worsen nutritional deficiencies and symptoms associated with malabsorption.

A) The amount of blood pumped by the heart through the circulatory system in 1 minute.
This statement describes cardiac output, which is the volume of blood pumped by the heart in one minute. Cardiac output is not directly related to the process of digestion.

B) Smooth muscle movement of the GI tract by way of contractions.
This statement describes peristalsis, which is the rhythmic contraction of smooth muscles in the GI tract that propels food and digestive contents through the digestive system. While peristalsis is an essential aspect of digestion, it does not encompass the entire process.

C) Neutralization by use of bicarbonate from pancreatic and biliary secretions.
This statement describes the role of bicarbonate in neutralizing stomach acid in the small intestine. Bicarbonate is released from pancreatic and biliary secretions to neutralize acidic chyme from the stomach, creating a more favorable environment for digestive enzymes to function. While this is an important aspect of digestion, it does not fully encompass the entire process.

D) It is the process when food is broken down into molecules that can be absorbed.
Digestion refers to the process by which food is broken down into smaller molecules that can be absorbed and utilized by the body. This process occurs in the gastrointestinal (GI) tract and involves the mechanical and chemical breakdown of food into nutrients such as carbohydrates, proteins, and fats, as well as vitamins and minerals. These nutrients are then absorbed across the lining of the GI tract and transported to cells throughout the body for energy, growth, and repair.