The practical nurse (PN) is preparing cefazolin 400 mg IM for a client with a gram-positive infection. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, for IM use, add 2 mL sterile water for injection. Total volume after reconstitution is 2.5 mL. After reconstitution, how many mL should be administered to the client? (Enter numeric value only. If rounding is required, round to the whole number, nearest tenths/hundredth).

To calculate the amount of darbepoetin alfa that the nurse should administer, you can use the following formula:

Dose (mL) = Amount prescribed (mcg) / Concentration (mcg/mL)

In this case:

Amount prescribed = 40 mcg
Concentration = 60 mcg/mL

Dose (mL) = 40 mcg / 60 mcg/mL = 2/3 mL

Now, you can convert 2/3 mL to decimal to make it easier to work with:

2/3 = 0.6667 mL

Rounded to one decimal place, the nurse should administer approximately 0.7 mL of darbepoetin alfa. So, the correct answer is 0.7 mL.

Choice A rationale:

Aspirin is not typically contraindicated in a client who has taken sildenafil unless there are specific contraindications or allergies. Aspirin is often used in the management of acute chest pain to help prevent blood clot formation.

Choice B rationale:

Heparin is not contraindicated solely because the client has taken sildenafil. Heparin is an anticoagulant commonly used in various clinical settings, including the management of certain cardiac conditions.

Choice C rationale:

Morphine is not necessarily contraindicated based solely on the client's use of sildenafil. Morphine can be used to relieve chest pain in some cases of acute coronary syndrome. However, its use should be carefully evaluated based on the client's overall clinical presentation.

Choice D rationale:

Nitroglycerin should be withheld in this scenario. Sildenafil is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It can potentiate the vasodilatory effects of nitroglycerin, leading to a severe drop in blood pressure. Concomitant use of nitroglycerin and sildenafil is contraindicated due to the risk of significant hypotension, which can be life-threatening.