A nurse is reviewing laboratory results for a client who has been taking amoxicillin-clavulanate (Augmentin) for a bacterial respiratory tract infection.

Which of the following findings should alert the nurse to a possible adverse effect of this medication? (Select all that apply.).

Choice A rationale:

Aspirin is not typically contraindicated in a client who has taken sildenafil unless there are specific contraindications or allergies. Aspirin is often used in the management of acute chest pain to help prevent blood clot formation.

Choice B rationale:

Heparin is not contraindicated solely because the client has taken sildenafil. Heparin is an anticoagulant commonly used in various clinical settings, including the management of certain cardiac conditions.

Choice C rationale:

Morphine is not necessarily contraindicated based solely on the client's use of sildenafil. Morphine can be used to relieve chest pain in some cases of acute coronary syndrome. However, its use should be carefully evaluated based on the client's overall clinical presentation.

Choice D rationale:

Nitroglycerin should be withheld in this scenario. Sildenafil is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It can potentiate the vasodilatory effects of nitroglycerin, leading to a severe drop in blood pressure. Concomitant use of nitroglycerin and sildenafil is contraindicated due to the risk of significant hypotension, which can be life-threatening.

Choice A rationale:

Emphasize that using safe sex practices removes the risk of STIs. Rationale: While promoting safe sex practices is essential in preventing STIs, this response is not directly addressing the client's situation. The client already reports having unprotected sex, so this choice does not provide relevant information or address the potential consequences.

Choice B rationale:

Explain that reinfections occur from sex with untreated partners. Rationale: This is the correct response. Syphilis is a sexually transmitted infection that can be treated with antibiotics, but reinfections can occur if sexual partners are not treated. This response provides essential information about the potential consequences of unprotected sex with untreated partners.

Choice C rationale:

Clarify that all STIs are transmitted through sexual intercourse. Rationale: While this statement is accurate in a general sense, it does not specifically address the client's situation or the risks associated with syphilis. It lacks the focus needed to educate the client effectively about their current situation.

Choice D rationale:

Provide counseling that most contraceptives protect against infection. Rationale: This response is inaccurate. Contraceptives primarily aim to prevent pregnancy, not protect against STIs. Therefore, it does not address the client's concern or provide relevant information about syphilis.