The practical nurse (PN) is preparing cefazolin 400 mg IM for a client with a gram-positive infection. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, for IM use, add 2 mL sterile water for injection. The total volume after reconstitution is 2.5 mL.
After reconstitution, how many mL should be administered to the client?
(Enter numeric value only. If rounding is required, round to the whole number, nearest tenths/hundredth).
The Correct Answer is ["1"]
The concentration of cefazolin after reconstitution can be calculated as follows: Concentration = Total amount of drug / Total volume after reconstitution
Since the available vial contains 1 gram (1000 mg) of cefazolin and the total volume after reconstitution is 2.5 mL, we can calculate the concentration:
Concentration = 1000 mg / 2.5 mL = 400 mg/mL
Therefore, after reconstitution, the concentration of cefazolin is 400 mg/mL.
To administer a dose of 400 mg, we divide the desired dose by the concentration: Volume to administer = Desired dose / Concentration
Volume to administer = 400 mg / 400 mg/mL = 1 mL
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Related Questions
Correct Answer is D
Explanation
While the use of cocaine and heroin can pose various health risks, including cardiovascular complications, respiratory problems, and infectious diseases, Hepatitis is particularly associated with injection drug use, such as heroin. Hepatitis is an inflammation of the liver that can be caused by viral infections, including Hepatitis B and C. Sharing contaminated needles or other drug paraphernalia increases the risk of contracting Hepatitis. These viral infections can lead to chronic liver disease, liver cirrhosis, and even liver cancer if left untreated. Therefore, among the options provided, Hepatitis is the greatest health risk for this client due to the mode of drug administration and associated risks of viral transmission.
A, B, and C- It's important to note that while diabetes, glaucoma, and hypertension are all significant health conditions, they are not directly associated with the use of cocaine and heroin as drugs of choice. However, individuals who engage in substance abuse may still be at risk for developing or exacerbating other health conditions due to the overall impact on their physical and mental well-being.
Correct Answer is C
Explanation
This is the priority action by the practical nurse (PN) because it can help identify and prevent a potential adverse reaction to the medication. A client who is reaching saturation with medication means that the client has reached the maximum level of medication in the blood that can produce the desired therapeutic effect. However, this also means that the client is at a higher risk of developing toxicity or side effects from the medication.
The PN should report the findings of muscle soreness, fatigue, and warm skin to the charge nurse, as these may indicate signs of inflammation, infection, or allergic reaction to the medication. The PN should also monitor the client's vital signs, oxygen saturation, and laboratory values, and document the findings. The charge nurse should notify the health care provider and adjust the medication dosage or regimen as ordered.
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