An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?

The patient experiences a decrease in hemoglobin S.

The patient experiences dehydration due to diuresis

The patient experiences an increase in fetal hemoglobin (Hbg F)

The patient needs fewer blood transfusions.

The patient experiences diuresis

Answer and Explanation

Correct Answer : C,D

A.   The patient experiences a decrease in hemoglobin S. Hydroxyurea does not decrease hemoglobin S levels directly; it works by increasing fetal hemoglobin (Hgb F) levels.
B.   The patient experiences dehydration due to diuresis. This is not an indication that Hydroxyurea is working; it is a potential side effect that should be monitored.
C.   The patient experiences an increase in fetal hemoglobin (Hbg F). Hydroxyurea works by increasing the levels of fetal hemoglobin, which reduces the sickling of red blood cells.
D.   The patient needs fewer blood transfusions. Successful treatment with Hydroxyurea should reduce the frequency of vaso-occlusive crises and the need for blood transfusions.
E.   The patient experiences diuresis. This is not an indicator of the medication's effectiveness; it is a potential side effect.

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Correct Answer is A

Explanation

A. Three to seven days after menses stops. This is the best time to perform BSE as the breasts are least likely to be swollen and tender during this period.
B. Prior to the beginning of menses. Breasts are more likely to be swollen and tender before menstruation, which can make it harder to detect abnormalities.
C. On the second day of menstruation. During menstruation, hormonal changes can affect breast tissue, making the examination less reliable.
D. On the same day every month. For those with regular menstrual cycles, it is recommended to perform BSE a few days after menses stops for more accurate results.

A. clotting B. Cyanosis C. Jaundice D. Bleeding

Correct Answer is C

Explanation

A. Clotting is not directly related to the destruction of red blood cells.
B. Cyanosis refers to a bluish discoloration of the skin due to poor circulation or inadequate oxygenation, which is not directly indicative of red blood cell destruction.
C. Jaundice is the yellowing of the skin and eyes caused by the buildup of bilirubin, a byproduct of the destruction of red blood cells, which is a common symptom of hemolytic anemia.
D. Bleeding is not a symptom associated with the destruction of red blood cells but rather a lack of clotting factors or platelets.

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An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is A

Explanation

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Correct Answer is C

Explanation

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