An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?

The patient experiences a decrease in hemoglobin S.

The patient experiences dehydration due to diuresis

The patient experiences an increase in fetal hemoglobin (Hbg F)

The patient needs fewer blood transfusions.

The patient experiences diuresis

Answer and Explanation

Correct Answer : C,D

A.   The patient experiences a decrease in hemoglobin S. Hydroxyurea does not decrease hemoglobin S levels directly; it works by increasing fetal hemoglobin (Hgb F) levels.
B.   The patient experiences dehydration due to diuresis. This is not an indication that Hydroxyurea is working; it is a potential side effect that should be monitored.
C.   The patient experiences an increase in fetal hemoglobin (Hbg F). Hydroxyurea works by increasing the levels of fetal hemoglobin, which reduces the sickling of red blood cells.
D.   The patient needs fewer blood transfusions. Successful treatment with Hydroxyurea should reduce the frequency of vaso-occlusive crises and the need for blood transfusions.
E.   The patient experiences diuresis. This is not an indicator of the medication's effectiveness; it is a potential side effect.

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Correct Answer is B

Explanation

A. Diarrhea: While diarrhea can occur in some cases of ovarian cancer, it is not one of the most common manifestations.
B. Unexplained weight loss: Unexplained weight loss is a common symptom of ovarian cancer and may be due to factors such as cancer-related cachexia or decreased appetite.
C. Urinary retention: Urinary retention is not a typical manifestation of ovarian cancer. Urinary symptoms may occur if the cancer spreads to nearby structures, but urinary retention is not
common.

D. Abdominal bloating: Abdominal bloating is a common symptom of ovarian cancer, often accompanied by feelings of fullness and increased abdominal girth. It is often one of the earliest and most noticeable symptoms of the disease.

A. Severe pain in the abdomen and joints B. Fever and chills C. Cough and shortness of breath D. Numbness and tingling in the extremities

Correct Answer is A

Explanation

A. Severe pain in the abdomen and joints. Severe pain is the hallmark symptom of a sickle cell crisis, often occurring in the abdomen, joints, and bones due to vaso-occlusive events.
B. Fever and chills. While fever can be a sign of infection in individuals with sickle cell disease, it is not the most common symptom during a sickle cell crisis.
C. Cough and shortness of breath. These symptoms are more indicative of respiratory infections or complications like acute chest syndrome but are not the primary symptoms of a sickle cell crisis.
D. Numbness and tingling in the extremities. These symptoms are not typically associated with a sickle cell crisis.

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An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse in a provider's office is collecting data from a client who has ovarian cancer. Which of the following manifestations should the nurse expect?

Correct Answer is B

Explanation

During a sickle cell crisis, which of the following symptoms is most commonly experienced by individuals with sickle cell disease?

Correct Answer is A

Explanation

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