A primary healthcare provider has prescribed ertapenem to a 6-year-old child with a urinary tract infection (UTI).
What is the safe dose of medication for this child?

To find the amount of solution to draw for one dose, you need to calculate the following:

- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)

First, use the formula for BSA to find the client's body surface area in square meters:

BSA (m²) = √(Height (cm) x Weight (kg) / 3600)

Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:

BSA (m²) = √(148 cm x 55 kg / 3600)

Simplify and solve for the BSA:

BSA (m²) = 1.41 m²

Next, use the formula for dose to find the amount of allopurinol in milligrams:

Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)

Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:

Dose (mg) = 1.41 m² x 115 mg/m²

Simplify and solve for the dose:

Dose (mg) = 162.15 mg

Then, use the formula for volume to find the amount of solution in milliliters:

Volume (mL) = Dose (mg) / Concentration (mg/mL)

Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:

Volume (mL) = 162.15 mg / 25 mg/mL

Simplify and solve for the volume:

Volume (mL) = 6.486 mL

Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.

The amount of ampicillin in one dose is 390 mg.

This answer is correct because it is based on a series of multiplication and division calculations. The nurse should follow these steps to determine the amount of ampicillin in one dose:

1) Multiply the prescribed dose per kilogram per day by the child's weight in kilograms to get the total dose per day in milligrams, as follows:

150 mg/kg/day x 10.4 kg = 1560 mg/day

Therefore, the child needs 1560 mg of ampicillin per day.

2) Divide the total dose per day by the number of doses per day to get the amount of each dose in milligrams, as follows:

1560 mg/day / 4 doses/day = 390 mg/dose

Therefore, the amount of ampicillin in one dose is 390 mg.