A nurse needs to infuse esmolol to a patient weighing 65 kg. The dose on hand is 2,500 mg esmolol in 250 mL of fluid. The patient requires a dose of 200 mcg/kg/min to control a hypertensive crisis. Which rate should the nurse calculate to infuse this medication? Round to the nearest whole number.
78 mL/hr
105 mL/hr
60 mL/hr
16 mL/hr
The Correct Answer is A
To calculate the infusion rate, we need to convert the patient's weight from kilograms to milligrams.
Patient's weight: 65 kg
Dose required: 200 mcg/kg/min
First, let's calculate the total dose required for the patient per minute: Dose required = 200 mcg/kg/min * 65 kg
= 13,000 mcg/min
Next, we need to convert the dose from micrograms to milligrams:
13,000 mcg/min = 13 mg/min
Now, let's determine the infusion rate. We have 2,500 mg of esmolol in 250 mL of fluid. Therefore, the concentration of esmolol in the fluid is:
Concentration = 2,500 mg / 250 mL
= 10 mg/mL
To find the infusion rate, we divide the dose required by the concentration: Infusion rate = 13 mg/min / 10 mg/mL
= 1.3 mL/mi
Since the options are in mL/hr, we need to convert the rate from mL/min to mL/hr:
1.3 mL/min * 60 min/hr = 78 mL/hr
Therefore, the correct answer is:
a. 78 mL/hr
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Related Questions
Correct Answer is D
Explanation
To find the milliliters to administer, you need to use the formula for dosage calculation:
Volume (mL) = Dose ordered (mg) / Dose available (mg) x Volume available (mL)
Since the dose ordered is 275 mg, the dose available is 500 mg, and the volume available is 2 mL, plug in these values into the formula:
Volume (mL) = 275 mg / 500 mg x 2 mL
Simplify and solve for the volume:
Volume (mL) = 1.1 mL
Therefore, the nurse should administer **1.1 mL** of Primaxin to the patient.
Correct Answer is C
Explanation
This answer is correct because BSA is the most accurate method for calculating the child's dose from the adult dose¹². BSA takes into account the child's weight and height, and reflects the physiological function and organ growth of the child beter than weight alone¹. BSA can be calculated using a nomogram or a formula based on the child's weight and height¹. The child's dose can then be calculated by multiplying the adult dose by the ratio of the child's BSA to the average adult BSA (1.73 m2)¹. For example:
Child dose by BSA = (mg/day) = Adult Dose in mg/day x BSA in m2 / 1.73
OR
Child dose by BSA = (mg/day) = Adult Dose in mg/m2 x BSA in m2
The other options are not correct because they are not accurate methods for calculating the child's dose from the adult dose. Actual body weight and ideal body weight may not account for individual variations in pharmacokinetics, pharmacodynamics, or clinical response. Actual body height is not a reliable indicator of drug dosage, as it does not reflect the body mass or organ function of the child.
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