A patient is taking a monoamine oxidase inhibitor for depression. In planning care for this patient, the nurse knows that a hypertensive crisis may be possible and plans on having what drug on hand as an antidote?
Meperidine (Demerol)
Calcium channel blockers
Carbamazepine (Tegretol)
Dextromethorphan
The Correct Answer is B
A. Meperidine is contraindicated with monoamine oxidase inhibitors (MAOIs) and can lead to serotonin syndrome rather than being an antidote for hypertensive crisis.
B. Calcium channel blockers, such as nifedipine, are commonly used as antidotes for hypertensive crisis associated with MAOI use.
C. Carbamazepine is not indicated for the treatment of hypertensive crisis associated with MAOI use.
D. Dextromethorphan is contraindicated with MAOIs due to the risk of serotonin syndrome.
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Related Questions
Correct Answer is D
Explanation
Explanation:
A. Adequate hydration is important to prevent lithium toxicity; decreasing fluid intake is not recommended.
B. Constipation can slow the excretion of lithium and may increase the risk of toxicity, but it is not the most appropriate preventive measure.
C. Sudden changes in sodium intake can affect lithium levels, so restricting sodium-rich foods without medical advice is not advisable.
D. Clients should be cautious with physical activity in hot weather, as excessive sweating can lead to dehydration, increasing the risk of lithium toxicity.
Correct Answer is B
Explanation
A. Bile acid agents primarily work by binding to bile acids in the intestines, leading to increased excretion of bile acids and cholesterol, but they are not specifically indicated for reducing triglyceride levels.
B. Fibric acid agents, such as gemfibrozil and fenofibrate, are considered the drug of choice for decreasing triglyceride levels, primarily by increasing the breakdown of triglyceride-rich particles and reducing hepatic triglyceride production.
C. HMG-CoA reductase inhibitors (statins) primarily lower LDL cholesterol levels but may also have modest effects on triglyceride levels.
D. Statins primarily target LDL cholesterol levels and are not considered the first-line therapy specifically for reducing triglyceride levels.
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