A patient is taking a monoamine oxidase inhibitor for depression. In planning care for this patient, the nurse knows that a hypertensive crisis may be possible and plans on having what drug on hand as an antidote?

Meperidine (Demerol)

Calcium channel blockers

Carbamazepine (Tegretol)

Dextromethorphan

Answer and Explanation

The Correct Answer is B

A. Meperidine is contraindicated with monoamine oxidase inhibitors (MAOIs) and can lead to serotonin syndrome rather than being an antidote for hypertensive crisis.

B. Calcium channel blockers, such as nifedipine, are commonly used as antidotes for hypertensive crisis associated with MAOI use.

C. Carbamazepine is not indicated for the treatment of hypertensive crisis associated with MAOI use.

D. Dextromethorphan is contraindicated with MAOIs due to the risk of serotonin syndrome.

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Correct Answer is C

Explanation

A. GABA (gamma-aminobutyric acid) is not typically targeted by antidepressants.

B. While some antidepressants may indirectly affect epinephrine and norepinephrine levels, the primary mechanism of action for most antidepressants is through increasing levels of serotonin and/or norepinephrine.

C. Antidepressants commonly work by increasing the levels of neurotransmitters such as norepinephrine and serotonin in the brain.

D. The reticular formation is not directly involved in the mechanism of action of antidepressants.

A. Naproxen B. Isosorbide C. Metformin D. Cefuroxime

Correct Answer is B

Explanation

A. Naproxen does not typically interact with sildenafil.

B. Sildenafil interacts with nitrates such as isosorbide, leading to severe hypotension, making it contraindicated in patients taking nitrates.

C. Metformin does not typically interact with sildenafil.

D. Cefuroxime does not typically interact with sildenafil.

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A patient is taking a monoamine oxidase inhibitor for depression. In planning care for this patient, the nurse knows that a hypertensive crisis may be possible and plans on having what drug on hand as an antidote?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient asks how most antidepressants work. The nurse responds by saying that antidepressants improve mood by increasing levels of:

Correct Answer is C

Explanation

A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil (Viagra). The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?

Correct Answer is B

Explanation

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