In the treatment of angina, the mechanism of action of an organic nitrate is:
Increased contractility and heart rate.
Slowed heart rate and decreased contractility of the heart.
Relaxation of arterial and venous smooth muscle.
Increased peripheral resistance.
The Correct Answer is C
A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.
B. Organic nitrates do not slow heart rate or decrease contractility of the heart.
C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.

D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Orange juice does not interact with simvastatin and does not need to be avoided.
B. Coenzyme Q10 (CoQ10) supplements are sometimes taken by patients on statins to help alleviate the side effects like muscle pain, but they do not need to be avoided.
C. Grapefruit juice should be avoided while taking simvastatin because it contains compounds that interfere with the enzymes that metabolize statins, potentially leading to increased drug levels and greater risk of side effects such as muscle damage.
D. Not all fruit juices interact with simvastatin; the specific concern is with grapefruit juice.
Correct Answer is A
Explanation
A. Fever is one of the hallmark symptoms of serotonin syndrome, along with other signs such as agitation, confusion, rapid heart rate, dilated pupils, and sweating.
B. Tinnitus is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.
C. Bruising is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.
D. Rash is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.
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