In the treatment of angina, the mechanism of action of an organic nitrate is:
Increased contractility and heart rate.
Slowed heart rate and decreased contractility of the heart.
Relaxation of arterial and venous smooth muscle.
Increased peripheral resistance.
The Correct Answer is C
A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.
B. Organic nitrates do not slow heart rate or decrease contractility of the heart.
C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.
D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Explanation:
A. Beta blockers are used to manage blood pressure and heart rate but are a different class.
B. Isosorbide is a nitrate, which is used primarily to treat and prevent episodes of angina by relaxing and widening blood vessels.
C. Calcium channel blockers also manage blood pressure and chest pain but act through a different mechanism.
D. Glycoprotein IIb/IIIa receptor antagonists are used to prevent platelet aggregation and are typically used in acute coronary syndrome, not as a long-term treatment for angina.
Correct Answer is B
Explanation
A. Multiple sclerosis is a chronic autoimmune disease affecting the central nervous system, not caused by statins or involving muscle inflammation.
B. Rhabdomyolysis is the breakdown of muscle tissue that leads to the release of muscle fiber contents into the bloodstream. It can be caused by statin medications among other factors.
C. Dystonia is a movement disorder characterized by involuntary muscle contractions, unrelated to muscle breakdown.
D. Spasticity is a condition where certain muscles are continuously contracted, causing stiffness or tightness of the muscles, also unrelated to muscle breakdown.
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