A nurse is teaching a client who has rheumatoid arthritis about taking methotrexate. Which of the following information should the nurse include?
Take an antiemetic 1 hr following administration.
Take the medication with an NSAID.
Drink 2 to 3 L Of water per day.
Rinse mouth 2 times per day with an alcohol-based mouthwash.
The Correct Answer is C
Methotrexate causes hyperuricemia which may predispose to kidney stones. Adequate hydration help flush out the uric acid preventing stone formation
A-Although methotrexate can cause nausea and vomiting, this does not always happen, therefore, no need for the antiemetic before intake
B-Taking methotrexate with an NSAID increases risk of gastrointestinal irritation
D-Methotrexate cause stomatitis which may be aggravated by use of alcohol-based mouth wash
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Rationale- Grape fruit inhibits the action of intestinal enzymes interfering with absorption and actions of most drugs. It is therefore, important for clients on oral medication to avoid the intake of grape fruit to allow optimal absorption of the drugs.
A, B, D- Have very minimal drug interactions and hence safe to take with most medications
Correct Answer is D
Explanation
Ciprofloxacin is a fluoroquinolone antibiotic that is associated with tendon rupture and tendonitis especially involving the Achilles tendon. Informing the client to report any tendon pain ensure that any complication is addressed and the medications stopped if need be.
A. ciprofloxacin causes diplopia and blurred vision but does not cause photophobia hence no need for sunglasses
B. The client should increase hydration as organism in UTI can predispose to urolithiasis
C. Antacids containing aluminum, magnesium, or calcium can interfere with the absorption of ciprofloxacin, reducing its effectiveness. They should be taken at least 2 hours before or 6 hours after taking the medication.
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