A nurse is reviewing the medication history of a client who has a new prescription for colchicine. Which of the following medications increases the client's risk when used in combination with colchicine for developing rhabdomyolysis?

Omeprazole

Hydrochlorothiazide

Carvedilol

Atorvastatin

Answer and Explanation

The Correct Answer is D

D. Atorvastatin is a statin medication used to lower cholesterol levels and reduce the risk of cardiovascular events. Statins, including atorvastatin, have been associated with an increased risk of rhabdomyolysis, particularly when used in high doses or in combination with other medications that can interact to increase statin levels in the blood.

A. There is no direct evidence to suggest that omeprazole increases the risk of rhabdomyolysis when used in combination with colchicine.

B. There is limited evidence to suggest that hydrochlorothiazide significantly increases the risk of rhabdomyolysis when used in combination with colchicine.

C. There is no direct evidence to suggest that carvedilol increases the risk of rhabdomyolysis when used in combination with colchicine.

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Correct Answer is D

Explanation

D. Tachypnea is a classic early manifestation of fat embolism syndrome. Fat emboli can travel to the lungs and obstruct blood flow, leading to respiratory distress and hypoxemia. Tachypnea is the body's response to hypoxemia, as it attempts to increase oxygen intake by breathing more rapidly.

A. Swelling of the calf can occur with conditions such as deep vein thrombosis (DVT), but it is not typically an early manifestation of fat embolism syndrome.

B. tachycardia is more commonly seen due to the body's response to decreased oxygen levels and increased demand on the cardiovascular system.

C. Hypertension is not typically associated with fat embolism syndrome. Instead, hypotension can occur due to decreased cardiac output and systemic vasodilation in severe cases of fat embolism syndrome.

A. Hold opioid analgesics until the patient is warmer. B. Notify the anesthesia care provider. C. Cover the patient with a warm blanket. D. Give acetaminophen 650 mg suppository rectally.

Correct Answer is C

Explanation

C. Covering the patient with a warm blanket is an appropriate initial intervention to address the patient's hypothermia and shivering. Heat conservation measures, such as using blankets or warming devices, help raise the patient's body temperature and alleviate shivering.

A. While shivering and a low body temperature (hypothermia) can be common postoperative complications, holding opioid analgesics may not directly address the underlying cause of the shivering or hypothermia.

B. Notifying the anesthesia care provider is a prudent action, especially if the patient's shivering and hypothermia are suspected to be related to intraoperative factors such as inadequate warming or anesthesia-induced temperature dysregulation. However, this is not the immediate action.

D. Acetaminophen is not typically indicated as the initial treatment for hypothermia or shivering. While acetaminophen can help reduce fever and discomfort, rectal suppositories may not provide rapid temperature elevation or relief from shivering.

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A nurse is reviewing the medication history of a client who has a new prescription for colchicine. Which of the following medications increases the client's risk when used in combination with colchicine for developing rhabdomyolysis?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is teaching a client who has a pelvic fracture about manifestations of fat embolism syndrome. The nurse should include which of the following findings as an early manifestation?

Correct Answer is D

Explanation

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Correct Answer is C

Explanation

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