A nurse is teaching a client who has a new prescription for cyclosporine oral solution to treat rheumatoid arthritis. Which of the following information should the nurse include in the teaching?
Take with grapefruit juice.
Mix with chocolate milk
Use a plastic container to mix.
Take the medication between meals.
None
None
The Correct Answer is D
D. Cyclosporine is typically taken on an empty stomach, either 1 hour before or 2 hours after a meal, to improve absorption. Taking it with food, especially high-fat meals, can decrease absorption and effectiveness.
A. Grapefruit juice can interact with cyclosporine, leading to increased blood levels of the medication and potentially causing toxicity. Therefore, clients should be advised to avoid grapefruit juice when taking cyclosporine.
B. Mixing cyclosporine oral solution with chocolate milk or any other liquid should be done only if directed by the healthcare provider or as specified in the medication instructions.
C. Using a plastic container to mix the oral solution may reduce the risk of interaction compared to using metal or glass containers. However, it's important to follow the specific instructions provided with the medication.
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Related Questions
Correct Answer is C
Explanation
C. This information is important to communicate to the surgical and anesthesia team as it indicates a potential family history of adverse reactions to anesthesia. Family history of anesthesia-related complications, especially in close relatives, can influence the anesthetic plan and help mitigate potential risks during surgery.
A. Clear fluids, such as apple juice, are typically allowed up to 2 hours before surgery, but the specific fasting instructions may vary depending on the institution's protocol and the type of surgery planned.
B. This information provides insight into the patient's caffeine consumption habits but it is not typically considered a critical factor to communicate to the surgical and anesthesia team before surgery.
D. Knowing the duration of aspirin cessation allows the anesthesia team to assess the patient's coagulation status and adjust the perioperative management accordingly. However, it does not present immediate risks as significant as a family history of anesthetic complications.
Correct Answer is D
Explanation
D. Petechiae, which are small red or purple spots caused by bleeding under the skin, are a classic manifestation of fat embolism syndrome. They typically appear on the upper chest, axilla (armpit), and conjunctiva of the eyes. Petechiae result from the occlusion of small blood vessels by fat globules, leading to microvascular bleeding.

A Paresthesia distal to the fracture site is not a typical manifestation of fat embolism syndrome. Instead, paresthesia may suggest nerve compression or injury related to the fracture itself rather than fat emboli.
B Fever is not a specific manifestation of fat embolism syndrome. While fever can occur with various types of infections or inflammatory conditions, it is not a hallmark symptom of fat embolism.
C Swelling of the calf can occur with conditions such as deep vein thrombosis (DVT), which is a potential complication of lower limb fractures. However, it is not a typical manifestation of fat embolism syndrome.
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