A nurse is reviewing laboratory results for a client who is taking warfarin. Which of the following laboratory tests determines if the dose of medication is within the recommended target range?
Bleeding time
Factor VIII
aPTT
INR
The Correct Answer is D
Choice A reason: Bleeding time assesses platelet function, not warfarin’s anticoagulant effect. Warfarin inhibits vitamin K-dependent clotting factors, unrelated to platelets. Monitoring bleeding time does not reflect therapeutic anticoagulation levels, making it irrelevant for adjusting warfarin doses to prevent thrombosis or bleeding.
Choice B reason: Factor VIII, deficient in hemophilia A, is not affected by warfarin, which targets vitamin K-dependent factors (II, VII, IX, X). Measuring Factor VIII does not indicate warfarin’s efficacy, as it is unrelated to the drug’s mechanism, making it unsuitable for dose monitoring.
Choice C reason: aPTT monitors heparin’s effect on the intrinsic clotting pathway, not warfarin’s action on vitamin K-dependent factors. Warfarin requires INR for therapeutic monitoring, as aPTT is insensitive to its effects, making it inappropriate for assessing warfarin’s anticoagulation range in patients.
Choice D reason: INR standardizes prothrombin time, measuring warfarin’s effect on vitamin K-dependent clotting factors. It ensures therapeutic anticoagulation (e.g., INR 2-3), preventing thrombosis or bleeding. INR is the gold standard for warfarin monitoring, guiding dose adjustments for safe and effective therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","C","D"]
Explanation
Choice A reason: Suctioning the ET removes secretions obstructing airflow, increasing peak airway pressure. Mucus buildup narrows the airway, triggering alarms. Clearing secretions restores patency, reduces pressure, and prevents complications like atelectasis or hypoxia, critical for effective ventilation in mechanically ventilated clients.
Choice B reason: Verifying ET placement ensures the tube is in the trachea. Misplacement, like esophageal intubation, increases airway resistance, elevating peak pressure. Confirmation via capnography or X-ray prevents hypoxia, ensuring proper ventilation and safety in clients on mechanical ventilators.
Choice C reason: Checking for kinks in ventilator tubing addresses mechanical obstructions raising peak airway pressure. Kinks restrict airflow, triggering alarms. Straightening tubing restores normal gas delivery, reducing resistance and maintaining effective ventilation, preventing hypoxia in mechanically ventilated clients.
Choice D reason: Administering a bronchodilator relieves bronchospasm, a common cause of high peak airway pressure. Bronchoconstriction narrows airways, increasing resistance. Bronchodilators relax smooth muscles, improving airflow and reducing pressure, addressing reversible causes like asthma in ventilated clients.
Choice E reason: Increasing tidal volume exacerbates high peak airway pressure, risking barotrauma or lung injury by forcing air against resistance. Addressing underlying causes like secretions or bronchospasm is safer, as higher volumes do not resolve the root issue, potentially worsening outcomes.
Correct Answer is C
Explanation
Choice A reason: Touching the inner surface of a sterile drape first contaminates it, as only sterile gloves should contact this area. Outer edges are handled to maintain sterility, so this action violates sterile technique, making it incorrect.
Choice B reason: Placing items within a 1-inch border of the drape is incorrect, as this border is considered non-sterile. Sterile items must be placed centrally to avoid contamination, so this action breaches sterile field principles, making it incorrect.
Choice C reason: Holding sterile instruments above the waist and away from the body maintains sterility, as areas below the waist or close to the body are considered contaminated. This aligns with aseptic technique, making it the correct action for sterile field preparation.
Choice D reason: Pouring solution from 12 inches above risks splashing, contaminating the sterile field. Solutions should be poured from 4-6 inches to control flow and maintain sterility, so this action is incorrect and unsafe for sterile procedures.
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