A nurse is preparing to administer medications to a client who states. "I don't want to take those drugs.’ Which of the following actions should the nurse take?

The correct answer is choiceb. Monitor the serum medication levels.

Choice A rationale:

Administering gentamicin with food is not necessary and does not minimize the risk of adverse effects. Gentamicin is typically given intravenously or intramuscularly, and food does not impact its administration or absorption.

Choice B rationale:

Monitoring the serum medication levels is crucial when administering gentamicin. Gentamicin has a narrow therapeutic index, meaning the difference between a therapeutic dose and a toxic dose is small. Regular monitoring helps ensure the drug remains within the safe and effective range, reducing the risk of nephrotoxicity and ototoxicity.

Choice C rationale:

Limiting the client’s fluid intake is not recommended. Adequate hydration is important to help prevent nephrotoxicity, a known adverse effect of gentamicin. Ensuring the client has sufficient fluid intake can help protect kidney function.

Choice D rationale:

Instructing the client to report agitation is not directly related to minimizing the risk of adverse effects of gentamicin. While it is important for clients to report any unusual symptoms, agitation is not a common adverse effect of gentamicin. Monitoring for signs of nephrotoxicity (e.g., decreased urine output) and ototoxicity (e.g., hearing loss, tinnitus) is more relevant.

An allergic reaction can occur in response to medication, and oxacillin is known to have the potential for causing allergic reactions. Symptoms of an allergic reaction may include rash, hives, itching, swelling, difficulty breathing, and anaphylaxis. Fever, amber urine, and diarrhoea are not typically associated with an allergic reaction to oxacillin.

Therefore, the nurse should monitor the client for any signs of an allergic reaction, particularly pruritus or itching, and report them to the healthcare provider promptly.