A nurse is preparing to administer belimumab 10 mg/kg via intermittent IV bolus to a client who weighs 136 lb. Available is belimumab 80 mg/mL. How many mL should the nurse administer?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
The Correct Answer is ["8"]
To calculate the amount of belimumab that the nurse should administer, we can use the following steps:
Convert the patient's weight from pounds to kilograms.
Multiply the patient's weight in kilograms by the dosage of belimumab (10 mg/kg) to find the total dosage required.
Determine the volume of the drug needed using the concentration of the available belimumab solution.
Given:
Patient's weight = 136 lb
Dosage of belimumab = 10 mg/kg
Available concentration of belimumab = 80 mg/mL
Let's calculate step by step:
Convert patient's weight from pounds to kilograms:
Patient's weight in kg = 136 lb × (1 kg / 2.2 lb) ≈ 61.8 kg
Calculate the total dosage required:
Total dosage = 10 mg/kg × 61.8 kg ≈ 618 mg
Determine the volume of the drug needed using the concentration of the available belimumab solution:
Volume of drug = Total dosage / Concentration of belimumab
Volume of drug = 618 mg / 80 mg/mL ≈ 7.7 mL
Rounding to the nearest whole number, the nurse should administer 8 mL of the belimumab.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Elimination is the process of removing a drug from the body, usually through the kidneys or the liver. Acute renal failure is a condition where the kidneys suddenly lose their ability to filter waste products and excess fluid from the blood. This can impair the elimination of drugs that are mainly excreted by the kidneys, leading to increased drug levels and potential toxicity. The nurse should monitor the patient's renal function and adjust the dose of drugs that are renally eliminated.
Choice B reason: Metabolism is the process of transforming a drug into one or more metabolites, usually by enzymes in the liver. Acute renal failure does not directly affect the metabolism of drugs, unless it causes liver damage or alters the blood flow to the liver. The nurse should monitor the patient's liver function and the levels of drugs that are metabolized by the liver.
Choice C reason: Distribution is the process of transferring a drug from the blood to the tissues and organs of the body. Acute renal failure can affect the distribution of drugs that are bound to plasma proteins, such as albumin. When the kidneys are damaged, they may leak protein into the urine, causing hypoalbuminemia (low levels of albumin in the blood). This can increase the amount of free or unbound drug in the blood, which may enhance the drug's effect or cause adverse reactions. The nurse should monitor the patient's serum albumin level and the effects of drugs that are highly protein bound.
Choice D reason: Absorption is the process of moving a drug from the site of administration to the bloodstream. Acute renal failure does not directly affect the absorption of drugs, unless it causes changes in the gastrointestinal tract, such as edema, bleeding, or motility disorders. The nurse should monitor the patient's gastrointestinal function and the bioavailability of drugs that are administered orally.
Correct Answer is ["0.71"]
Explanation
To calculate how many milliliters (mL) of the reconstituted medication the nurse should administer, we can use the following formula:
Desired dose (in mg) / Stock concentration (in mg/mL) = Volume to administer (in mL)
Given information:
Desired dose of ceftriaxone: 250 mg
Stock concentration after reconstitution: 350 mg/mL
Now let's calculate the volume to administer:
250 mg / 350 mg/mL = 0.7143 mL
Rounding to the nearest hundredth, the nurse should administer 0.71 mL of the reconstituted medication.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.