Which of the following would the nurse recognize as ACE inhibitors? SELECT ALL THAT APPLY
Captopril
Lisinopril
Atenolol
Labetalol
Ramipril
Correct Answer : A,B,E
Choice A reason: Captopril is an ACE inhibitor, which means it blocks the enzyme that converts angiotensin I to angiotensin II, a hormone that constricts blood vessels and raises blood pressure. Captopril is used to treat high blood pressure, heart failure, diabetic kidney disease, and some types of heart attack. ¹
Choice B reason: Lisinopril is also an ACE inhibitor, with similar effects and uses as captopril. Lisinopril may be preferred over captopril because it has a longer duration of action and fewer side effects. ²
Choice C reason: Atenolol is not an ACE inhibitor, but a beta blocker, which means it blocks the receptors for adrenaline and noradrenaline, hormones that increase heart rate and blood pressure. Atenolol is used to treat high blood pressure, angina, irregular heartbeat, and prevent heart attack and stroke. ³
Choice D reason: Labetalol is also not an ACE inhibitor, but a combination of alpha and beta blocker, which means it blocks both the receptors for adrenaline and noradrenaline, and the receptors for angiotensin II. Labetalol is used to treat high blood pressure, especially in pregnancy and hypertensive emergencies.
Choice E reason: Ramipril is another ACE inhibitor, with similar effects and uses as captopril and lisinopril. Ramipril may have additional benefits in preventing cardiovascular events and kidney damage in high-risk patients..
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Elimination is the process of removing a drug from the body, usually through the kidneys or the liver. Acute renal failure is a condition where the kidneys suddenly lose their ability to filter waste products and excess fluid from the blood. This can impair the elimination of drugs that are mainly excreted by the kidneys, leading to increased drug levels and potential toxicity. The nurse should monitor the patient's renal function and adjust the dose of drugs that are renally eliminated.
Choice B reason: Metabolism is the process of transforming a drug into one or more metabolites, usually by enzymes in the liver. Acute renal failure does not directly affect the metabolism of drugs, unless it causes liver damage or alters the blood flow to the liver. The nurse should monitor the patient's liver function and the levels of drugs that are metabolized by the liver.
Choice C reason: Distribution is the process of transferring a drug from the blood to the tissues and organs of the body. Acute renal failure can affect the distribution of drugs that are bound to plasma proteins, such as albumin. When the kidneys are damaged, they may leak protein into the urine, causing hypoalbuminemia (low levels of albumin in the blood). This can increase the amount of free or unbound drug in the blood, which may enhance the drug's effect or cause adverse reactions. The nurse should monitor the patient's serum albumin level and the effects of drugs that are highly protein bound.
Choice D reason: Absorption is the process of moving a drug from the site of administration to the bloodstream. Acute renal failure does not directly affect the absorption of drugs, unless it causes changes in the gastrointestinal tract, such as edema, bleeding, or motility disorders. The nurse should monitor the patient's gastrointestinal function and the bioavailability of drugs that are administered orally.
Correct Answer is ["25"]
Explanation
To calculate the IV flow rate in drops per minute (gtt/min) for the administration of clindamycin, we can follow these steps:
First, we need to determine the total number of minutes for the infusion, which is given as 1 hour:
1 hour × 60 minutes/hour = 60 minutes
Next, we calculate the total number of drops needed for the infusion:
The total volume to be infused is 100 mL.
The drop factor is 15 gtt/mL.
100 mL × 15 gtt/mL = 1500 gtt
Calculate the IV flow rate in drops per minute:
1500 gtt ÷ 60 min = 25 gtt/min
Rounding to the nearest whole number, the nurse should set the IV flow rate to deliver 25 gtt/min.
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