A nurse is monitoring a client who is receiving a unit of packed RBCs following surgery. Which of the following assessments is an indication that the client might be experiencing a hemolytic reaction?

Choice A reason: Using an electric razor while on warfarin is the correct instruction. Warfarin is an anticoagulant that inhibits the formation of blood clots and prolongs the bleeding time. Using an electric razor can reduce the risk of cuts and bleeding while shaving. The client should avoid using sharp objects or instruments that can cause injury or trauma.

Choice B reason: Doubling the dose of warfarin if a dose is missed is not the correct instruction. This is a dangerous and potentially fatal advice, as it can cause overdose and severe bleeding. The client should take the missed dose as soon as possible, unless it is close to the next scheduled dose, in which case the client should skip the missed dose and resume the regular dosing schedule. The client should never take extra doses or change the dose without consulting the provider.

Choice C reason: Mild nosebleeds being common during initial treatment is not the correct instruction. This is a false and misleading statement, as nosebleeds are not a normal or expected side effect of warfarin therapy. Nosebleeds can indicate bleeding problems or complications, such as thrombocytopenia, which is a low platelet count. The client should report any nosebleeds or other signs of bleeding, such as bruising, petechiae, hematuria, or melena, to the provider immediately.

Choice D reason: Increasing fiber intake to reduce the adverse effect of constipation is not the correct instruction. This is an irrelevant and unnecessary recommendation, as constipation is not a common or serious adverse effect of warfarin therapy. Constipation can be caused by many factors, such as diet, hydration, activity, or medication. The client should maintain a balanced and consistent diet, drink plenty of fluids, and exercise regularly to prevent constipation. The client should also avoid foods that are high in vitamin K, such as green leafy vegetables, as they can interfere with the effect of warfarin.

Choice A reason: Infection is the correct condition that the client is at increased risk for. Agranulocytosis is a severe decrease in the number of granulocytes, which are a type of white blood cell that fight infection. Propylthiouracil is an antithyroid drug that can cause agranulocytosis as a rare but serious side effect. The client with agranulocytosis is more susceptible to bacterial and fungal infections, and may present with fever, sore throat, mouth ulcers, and skin lesions.

Choice B reason: Excessive bleeding is not the correct condition that the client is at increased risk for. Agranulocytosis does not affect the platelets, which are the blood cells that help with clotting. Propylthiouracil does not cause bleeding disorders, although it may interact with anticoagulants and increase their effect.

Choice C reason: Hyperglycemia is not the correct condition that the client is at increased risk for. Agranulocytosis does not affect the insulin, which is the hormone that regulates blood glucose levels. Propylthiouracil does not cause hyperglycemia, although it may interfere with the metabolism of oral hypoglycemic agents and decrease their effect.

Choice D reason: Ecchymosis is not the correct condition that the client is at increased risk for. Ecchymosis is a bruise caused by bleeding under the skin. Agranulocytosis does not cause ecchymosis, as it does not affect the blood vessels or the platelets. Propylthiouracil does not cause ecchymosis, although it may increase the risk of skin rash and pruritus.