A nurse is assessing a client who has hypercholesterolemia and is receiving simvastatin. Which of the following findings should the nurse recognize as a potential adverse effect?
Blurred vision
Orthostatic hypotension
Urinary retention
Muscle weakness
The Correct Answer is D
Choice A reason: Blurred vision is not a common or serious side effect of simvastatin, as it does not affect the eyes or the vision. Blurred vision may be caused by other factors, such as diabetes, hypertension, or eye disorders.
Choice B reason: Orthostatic hypotension is not a common or serious side effect of simvastatin, as it does not affect the blood pressure or the vascular tone. Orthostatic hypotension may be caused by other factors, such as dehydration, anemia, or medication interactions.
Choice C reason: Urinary retention is not a common or serious side effect of simvastatin, as it does not affect the urinary tract or the bladder function. Urinary retention may be caused by other factors, such as prostate enlargement, infection, or nerve damage.
Choice D reason: Muscle weakness is a common and serious side effect of simvastatin, as it can indicate muscle damage or rhabdomyolysis. Rhabdomyolysis is a life-threatening condition that causes the breakdown of muscle tissue and the release of myoglobin into the bloodstream, which can lead to kidney failure. Muscle weakness may be accompanied by muscle pain, tenderness, or dark urine. The nurse should monitor the client's creatine kinase (CK) levels and report any signs of muscle damage to the provider.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","D"]
Explanation
Choice A reason: Removing the patch for 10 to 12 hours daily is a correct instruction. This allows the client to have a nitrate-free period, which prevents the development of tolerance to the medication. Tolerance reduces the effectiveness of nitroglycerin in relieving anginal pain. The client should remove the patch at night, when the risk of angina is lower, and apply a new patch in the morning.
Choice B reason: Applying the patch to a hairless area and rotating sites is a correct instruction. This prevents skin irritation and enhances absorption of the medication. The client should avoid applying the patch to areas that are exposed to heat, sunlight, or friction, as these factors can increase the release of nitroglycerin and cause hypotension.
Choice C reason: Applying a new patch at the onset of anginal pain is not a correct instruction. Transdermal nitroglycerin is used for the prevention, not the treatment, of anginal attacks. The onset of action of transdermal nitroglycerin is slow, and it may take several hours to reach peak effect. The client should use sublingual nitroglycerin, which has a rapid onset of action, to treat acute anginal pain.
Choice D reason: Applying a new patch each morning is a correct instruction. This ensures that the client has a steady and adequate supply of nitroglycerin throughout the day, when the risk of angina is higher. The client should apply the patch to a different site each day, and remove the old patch before applying the new one.
Choice E reason: Applying the patch to dry skin and covering the area with plastic wrap is not a correct instruction. This can cause skin maceration, which is the softening and breaking down of the skin due to moisture. This can increase the risk of infection and reduce the absorption of the medication. The client should apply the patch to clean and dry skin, and avoid covering the area with any dressing or tape.

Correct Answer is C
Explanation
Choice A reason: Taking this medication with food is not necessary, as lisinopril can be taken with or without food. Food does not affect the absorption or effectiveness of lisinopril.
Choice B reason: Facial swelling is not an expected effect of this medication, but a serious adverse reaction that indicates angioedema. Angioedema is a life-threatening condition that causes swelling of the face, tongue, throat, and airway. It requires immediate medical attention and discontinuation of lisinopril.
Choice C reason: Reporting a cough to the provider is an important instruction, as a cough is a common and annoying side effect of lisinopril. Lisinopril belongs to the class of angiotensin-converting enzyme (ACE) inhibitors, which can cause a dry, persistent, nonproductive cough. The cough may interfere with the client's quality of life and adherence to the medication. The provider may prescribe an alternative medication, such as an angiotensin II receptor blocker (ARB), to avoid the cough.
Choice D reason: Increasing the intake of potassium-rich foods is not advisable, as lisinopril can cause hyperkalemia (high potassium levels) due to decreased potassium excretion in the urine. Clients should monitor their potassium levels and avoid excessive intake of potassium supplements or foods, such as bananas, oranges, potatoes, and tomatoes.
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