A nurse is completing a medical interview with a client who has elevated cholesterol levels and takes warfarin. The nurse should recognize that which of the following actions by the client can potentiate the effects of warfarin?
The client follows a low-fat diet to reduce cholesterol.
The client drinks a glass of grapefruit juice every day.
The client sprinkles flax seeds on food 1 hr before taking the anticoagulant.
The client uses garlic to lower cholesterol levels.
The Correct Answer is D
The correct answer is: d. The client uses garlic to lower cholesterol levels.
Choice A: The client follows a low-fat diet to reduce cholesterol
Following a low-fat diet to reduce cholesterol does not have a significant impact on the effects of warfarin. While diet can influence overall health and cholesterol levels, it does not directly interact with warfarin’s anticoagulant properties.
Choice B: The client drinks a glass of grapefruit juice every day
Grapefruit juice is known to interact with various medications by inhibiting the cytochrome P450 enzymes, particularly CYP3A4. However, grapefruit juice does not significantly affect warfarin metabolism. It is more commonly associated with interactions with statins and other medications.
Choice C: The client sprinkles flax seeds on food 1 hr before taking the anticoagulant
Flax seeds are rich in omega-3 fatty acids and fiber, which can be beneficial for heart health. However, there is no strong evidence to suggest that flax seeds significantly potentiate the effects of warfarin. They do not have a direct interaction with the anticoagulant properties of warfarin.
Choice D: The client uses garlic to lower cholesterol levels
Garlic is known to have antiplatelet properties, which can enhance the anticoagulant effects of warfarin. This can increase the risk of bleeding in clients taking warfarin. Garlic can interfere with the blood clotting process, making it a significant factor to consider when managing a client on warfarin.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Black cohosh is an herbal supplement that is used to treat menopausal symptoms, such as hot flashes and mood swings. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.
Choice B reason: Echinacea is an herbal supplement that is used to boost the immune system and prevent or treat common colds and infections. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.
Choice C reason: Feverfew is an herbal supplement that is used to treat migraines, arthritis, and fever. It has a significant interaction with warfarin and can increase the risk of bleeding and bruising. It can also reduce the effectiveness of warfarin and alter the client's international normalized ratio (INR).
Choice D reason: Flaxseed is an herbal supplement that is used to lower cholesterol, blood pressure, and inflammation. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.
Correct Answer is A
Explanation
Choice A reason: Infection is the correct condition that the client is at increased risk for. Agranulocytosis is a severe decrease in the number of granulocytes, which are a type of white blood cell that fight infection. Propylthiouracil is an antithyroid drug that can cause agranulocytosis as a rare but serious side effect. The client with agranulocytosis is more susceptible to bacterial and fungal infections, and may present with fever, sore throat, mouth ulcers, and skin lesions.
Choice B reason: Excessive bleeding is not the correct condition that the client is at increased risk for. Agranulocytosis does not affect the platelets, which are the blood cells that help with clotting. Propylthiouracil does not cause bleeding disorders, although it may interact with anticoagulants and increase their effect.
Choice C reason: Hyperglycemia is not the correct condition that the client is at increased risk for. Agranulocytosis does not affect the insulin, which is the hormone that regulates blood glucose levels. Propylthiouracil does not cause hyperglycemia, although it may interfere with the metabolism of oral hypoglycemic agents and decrease their effect.
Choice D reason: Ecchymosis is not the correct condition that the client is at increased risk for. Ecchymosis is a bruise caused by bleeding under the skin. Agranulocytosis does not cause ecchymosis, as it does not affect the blood vessels or the platelets. Propylthiouracil does not cause ecchymosis, although it may increase the risk of skin rash and pruritus.
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