A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

Acetylcholine and gamma-aminobutyric acid (GABA).

Glutamate and epinephrine.

Serotonin, dopamine, and norepinephrine.

Endorphins and oxytocin.

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Acetylcholine and gamma-aminobutyric acid (GABA) are not the primary neurotransmitters involved in regulating mood, motivation, reward, cognition, and stress response. Acetylcholine plays a role in memory and muscle control, while GABA is an inhibitory neurotransmitter that helps regulate anxiety and sleep. These neurotransmitters are not as closely associated with the functions mentioned in the question.

Choice B rationale:

Glutamate is a major excitatory neurotransmitter in the central nervous system, and epinephrine (also known as adrenaline) is a hormone that prepares the body for the fight-or-flight response. While both glutamate and epinephrine play important roles in various physiological responses, they are not primarily responsible for regulating mood, motivation, reward, cognition, and stress response as mentioned in the question.

Choice C rationale:

Serotonin, dopamine, and norepinephrine are all key neurotransmitters involved in the regulation of mood, motivation, reward, cognition, and stress response. These neurotransmitters have been extensively studied in the context of mood disorders like Major Depressive Disorder (MDD). Serotonin is often associated with feelings of well-being and happiness, dopamine is linked to pleasure and reward pathways, and norepinephrine is involved in the body's stress response. Imbalances in these neurotransmitters have been implicated in the development of mood disorders.

Choice D rationale:

Endorphins and oxytocin are important neurotransmitters, but they are not as directly related to the regulation of mood, motivation, reward, cognition, and stress response as the neurotransmitters mentioned in choice C. Endorphins are known for their role in pain modulation and feelings of pleasure, while oxytocin is often referred to as the "bonding hormone" and is associated with social connections and childbirth.

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Correct Answer is C

Explanation

Choice A rationale:

Bipolar disorder involves distinct periods of both elevated mood (mania or hypomania) and depressive episodes. The scenario describes persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia, which are characteristic symptoms of major depressive disorder (MDD) but not necessarily indicative of bipolar disorder.

Choice B rationale:

An adjustment disorder is characterized by emotional or behavioral symptoms that arise within three months of experiencing a stressor (e.g., a major life change or event). The persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia described in the scenario are beyond the typical time frame for an adjustment disorder.

Choice C rationale:

The correct answer. Major depressive disorder (MDD) is characterized by persistent feelings of sadness, loss of interest or pleasure, changes in weight or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, fatigue, feelings of worthlessness or excessive guilt, difficulty concentrating, and recurrent thoughts of death or suicide. The client's symptoms align closely with the diagnostic criteria for MDD.

Choice D rationale:

A normal response to stress usually involves transient feelings of sadness or anxiety in response to a stressor. However, the client's symptoms of persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia are indicative of a more serious and prolonged condition like major depressive disorder (MDD).

A. Positive life events. B. High income. C. Lack of social support. D. Optimistic thinking.

Correct Answer is C

Explanation

Choice A rationale:

Positive life events, although beneficial, are not typically considered contributors to the development of depression. Positive events generally have a positive impact on mental health and may even serve as protective factors against depression.

Choice B rationale:

High income is not commonly recognized as a direct contributor to depression. In fact, higher income can provide access to better resources and opportunities that might contribute to better mental health outcomes.

Choice C rationale:

Lack of social support is a well-established factor contributing to the development of depression. Social support plays a crucial role in buffering against stress and providing individuals with a sense of belonging and emotional connection. A lack of strong social ties can lead to feelings of isolation and increase vulnerability to depression.

Choice D rationale:

Optimistic thinking is typically considered a protective factor against depression rather than a contributor to its development. Optimistic thinking involves a positive outlook on life and the expectation of positive outcomes, which can act as a resilience factor against depressive symptoms.

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A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client is experiencing persistent feelings of sadness, guilt, and worthlessness. They also report significant weight loss and insomnia. The nurse suspects the client may have:

Correct Answer is C

Explanation

A client wants to understand the factors that contribute to the development of depression. Which of the following factors are mentioned in the text as potential contributors to depression?

Correct Answer is C

Explanation

A client is sharing their experiences with a nurse. The client states, "I just can't seem to enjoy anything anymore. Even activities I used to love don't bring me pleasure." This statement by the client is indicative of:

A client is concerned about the potential side effects of antidepressant medications. Which of the following side effects is commonly associated with antidepressant use?

(Select All That Apply): A nurse is assessing a client for major depressive disorder (MDD). Which of the following signs and symptoms are consistent with the clinical presentation of MDD? Select all that apply.

(Select All That Apply): A nurse is discussing the psychosocial factors that can affect or be affected by depression with a client. Which of the following factors are considered psychosocial factors related to depression? Select all that apply.

A nurse is assessing a client who has been experiencing persistent feelings of sadness, fatigue, and difficulty concentrating. The client denies any history of manic episodes. Which of the following conditions should the nurse consider as a possible differential diagnosis for this client?

A nurse is providing education to a group of nursing students about major depressive disorder (MDD). Which of the following statements accurately describes a characteristic of MDD?

A client asks a nurse about the differences between major depressive disorder (MDD) and dysthymia. Which of the following responses by the nurse is accurate?