A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?
Acetylcholine and gamma-aminobutyric acid (GABA).
Glutamate and epinephrine.
Serotonin, dopamine, and norepinephrine.
Endorphins and oxytocin.
The Correct Answer is C
Choice A rationale:
Acetylcholine and gamma-aminobutyric acid (GABA) are not the primary neurotransmitters involved in regulating mood, motivation, reward, cognition, and stress response. Acetylcholine plays a role in memory and muscle control, while GABA is an inhibitory neurotransmitter that helps regulate anxiety and sleep. These neurotransmitters are not as closely associated with the functions mentioned in the question.
Choice B rationale:
Glutamate is a major excitatory neurotransmitter in the central nervous system, and epinephrine (also known as adrenaline) is a hormone that prepares the body for the fight-or-flight response. While both glutamate and epinephrine play important roles in various physiological responses, they are not primarily responsible for regulating mood, motivation, reward, cognition, and stress response as mentioned in the question.
Choice C rationale:
Serotonin, dopamine, and norepinephrine are all key neurotransmitters involved in the regulation of mood, motivation, reward, cognition, and stress response. These neurotransmitters have been extensively studied in the context of mood disorders like Major Depressive Disorder (MDD). Serotonin is often associated with feelings of well-being and happiness, dopamine is linked to pleasure and reward pathways, and norepinephrine is involved in the body's stress response. Imbalances in these neurotransmitters have been implicated in the development of mood disorders.
Choice D rationale:
Endorphins and oxytocin are important neurotransmitters, but they are not as directly related to the regulation of mood, motivation, reward, cognition, and stress response as the neurotransmitters mentioned in choice C. Endorphins are known for their role in pain modulation and feelings of pleasure, while oxytocin is often referred to as the "bonding hormone" and is associated with social connections and childbirth.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","E"]
Explanation
Choice A rationale:
Social support refers to the network of family, friends, and community that provide emotional and practical assistance. Depression can be influenced by inadequate social support, as having a strong support system can buffer against the development and exacerbation of depressive symptoms.
Choice B rationale:
Personalization involves attributing external events to oneself, often in a negative manner. While this cognitive distortion is relevant to depression, it is not mentioned in the question stem and does not directly relate to cognitive processes influenced by depression.
Choice C rationale:
Cognitive distortions are irrational and negative thought patterns that are common in depression. These distortions contribute to the maintenance of depressive symptoms. Examples include all-or-nothing thinking, overgeneralization, and catastrophizing.
Choice D rationale:
Catastrophizing involves magnifying the negative significance of events. While it can contribute to depressive thought patterns, it is not as central to cognitive processes influenced by depression as cognitive distortions are.
Choice E rationale:
Interpersonal relationships are affected by depression and can also contribute to its development. The question does not focus on the effects of depression on relationships, but rather on the factors that can influence or be influenced by depression.
Correct Answer is D
Explanation
Choice A rationale:
Depression is not solely caused by genetic factors. While genetics do play a role in predisposing individuals to depression, it's a complex interplay between genetic susceptibility and environmental influences that contribute to the development of the disorder.
Choice B rationale:
Genetic factors are not minor players in depression. Research suggests that genetics can significantly influence a person's susceptibility to depression. However, environmental factors, such as trauma, stress, and life experiences, also contribute substantially to the onset and course of depression.
Choice C rationale:
The relationship between genetics and depression is not as straightforward as specific genes causing depression independently of environmental factors. Depression is a multifactorial disorder influenced by a combination of genetic, biological, psychological, and environmental factors.
Choice D rationale:
This is the correct answer. Genetic factors do contribute to an individual's vulnerability to depression. Studies of families, twins, and heritability have demonstrated a genetic component to depression. However, it's crucial to recognize that genetic predisposition interacts with environmental factors. Trauma, loss, chronic stress, and other environmental triggers can precipitate depressive episodes in genetically susceptible individuals.
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