A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

Acetylcholine and gamma-aminobutyric acid (GABA).

Glutamate and epinephrine.

Serotonin, dopamine, and norepinephrine.

Endorphins and oxytocin.

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Acetylcholine and gamma-aminobutyric acid (GABA) are not the primary neurotransmitters involved in regulating mood, motivation, reward, cognition, and stress response. Acetylcholine plays a role in memory and muscle control, while GABA is an inhibitory neurotransmitter that helps regulate anxiety and sleep. These neurotransmitters are not as closely associated with the functions mentioned in the question.

Choice B rationale:

Glutamate is a major excitatory neurotransmitter in the central nervous system, and epinephrine (also known as adrenaline) is a hormone that prepares the body for the fight-or-flight response. While both glutamate and epinephrine play important roles in various physiological responses, they are not primarily responsible for regulating mood, motivation, reward, cognition, and stress response as mentioned in the question.

Choice C rationale:

Serotonin, dopamine, and norepinephrine are all key neurotransmitters involved in the regulation of mood, motivation, reward, cognition, and stress response. These neurotransmitters have been extensively studied in the context of mood disorders like Major Depressive Disorder (MDD). Serotonin is often associated with feelings of well-being and happiness, dopamine is linked to pleasure and reward pathways, and norepinephrine is involved in the body's stress response. Imbalances in these neurotransmitters have been implicated in the development of mood disorders.

Choice D rationale:

Endorphins and oxytocin are important neurotransmitters, but they are not as directly related to the regulation of mood, motivation, reward, cognition, and stress response as the neurotransmitters mentioned in choice C. Endorphins are known for their role in pain modulation and feelings of pleasure, while oxytocin is often referred to as the "bonding hormone" and is associated with social connections and childbirth.

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Correct Answer is A

Explanation

Choice A rationale:

Patient Health naire (PHQ-9). The PHQ-9 is a commonly used depression assessment tool that evaluates a patient's mood and depressive symptoms. It consists of nine questions that correspond to the nine criteria for diagnosing major depressive disorder (MDD) according to the DSM-5. The tool assesses various aspects of depression, such as mood, sleep disturbances, appetite changes, and more. It's a self-report questionnaire that helps clinicians assess the severity of a patient's depression and track their progress over time.

Choice B rationale:

Hamilton Depression Rating Scale (HAM-D). The Hamilton Depression Rating Scale (HAM-D) is another widely used tool for assessing the severity of depressive symptoms in patients with mood disorders. It contains multiple items that evaluate various aspects of depression, such as mood, feelings of guilt, suicidal ideation, and more. Unlike the PHQ-9, the HAM-D is typically administered by a trained clinician and is more extensive, making it suitable for clinical research and diagnosis but potentially less practical for routine screening.

Choice C rationale:

Beck Depression Inventory (BDI). The Beck Depression Inventory (BDI) is a self-report questionnaire designed to assess the presence and severity of depressive symptoms in individuals. It consists of 21 multiple-choice questions that cover various emotional, cognitive, and physical symptoms of depression. The BDI is useful for assessing the intensity of depression and changes in symptom severity over time. While a valuable tool, it's not the assessment tool most likely used in this scenario.

Choice D rationale:

Mini-Mental State Examination (MMSE). The Mini-Mental State Examination (MMSE) is not an appropriate tool for assessing depression. Instead, it's a brief cognitive screening test used to assess cognitive impairment and cognitive decline in individuals, especially in older adults. It evaluates aspects such as orientation, memory, attention, language, and visuospatial skills. It is not designed to assess mood, anxiety, or other emotional aspects related to depression.

A. Bipolar disorder. B. An adjustment disorder. C. Major depressive disorder (MDD). D. A normal response to stress.

Correct Answer is C

Explanation

Choice A rationale:

Bipolar disorder involves distinct periods of both elevated mood (mania or hypomania) and depressive episodes. The scenario describes persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia, which are characteristic symptoms of major depressive disorder (MDD) but not necessarily indicative of bipolar disorder.

Choice B rationale:

An adjustment disorder is characterized by emotional or behavioral symptoms that arise within three months of experiencing a stressor (e.g., a major life change or event). The persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia described in the scenario are beyond the typical time frame for an adjustment disorder.

Choice C rationale:

The correct answer. Major depressive disorder (MDD) is characterized by persistent feelings of sadness, loss of interest or pleasure, changes in weight or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, fatigue, feelings of worthlessness or excessive guilt, difficulty concentrating, and recurrent thoughts of death or suicide. The client's symptoms align closely with the diagnostic criteria for MDD.

Choice D rationale:

A normal response to stress usually involves transient feelings of sadness or anxiety in response to a stressor. However, the client's symptoms of persistent feelings of sadness, guilt, worthlessness, weight loss, and insomnia are indicative of a more serious and prolonged condition like major depressive disorder (MDD).

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A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is administering a depression assessment tool to a client. The tool evaluates mood, anxiety, insomnia, somatic symptoms, and other aspects of depression. Which assessment tool is the nurse most likely using?

Correct Answer is A

Explanation

A client is experiencing persistent feelings of sadness, guilt, and worthlessness. They also report significant weight loss and insomnia. The nurse suspects the client may have:

Correct Answer is C

Explanation

(Select All That Apply): A nurse is providing care for a client with suspected major depressive disorder (MDD). Which of the following are risk factors for developing MDD? Select all that apply.

A nurse is conducting a mental health assessment on a client. The client reports feeling extremely fatigued, having difficulty concentrating, and having thoughts of worthlessness. The nurse recognizes these as:

(Select All That Apply): A nurse is educating a group of clients about the treatment approaches for MDD. Which of the following modalities are considered main treatment options for MDD according to the text? Select all that apply.

A nurse is assessing a client who has been experiencing persistent feelings of sadness, fatigue, and difficulty concentrating. The client denies any history of manic episodes. Which of the following conditions should the nurse consider as a possible differential diagnosis for this client?

(Select All That Apply): A nurse is teaching a group of nursing students about the diagnostic criteria for major depressive disorder (MDD) according to DSM-5. Which of the following are part of the diagnostic criteria? Select all that apply.

(Select All That Apply): A nurse is assessing a client for major depressive disorder (MDD). Which of the following signs and symptoms are consistent with the clinical presentation of MDD? Select all that apply.

(Select All That Apply): A nurse is educating a client about the psychosocial factors that can influence or be influenced by depression. Which of the following factors are associated with depression and its effects on cognitive processes? Select all that apply.