A nurse is discussing the various treatment approaches for Major Depressive Disorder (MDD) with a client. Which treatment modality involves stimulating the brain electrically or magnetically to induce changes in neuronal activity and neuroplasticity?

Choice A rationale:

Social support refers to the network of family, friends, and community that provide emotional and practical assistance. Depression can be influenced by inadequate social support, as having a strong support system can buffer against the development and exacerbation of depressive symptoms.

Choice B rationale:

Personalization involves attributing external events to oneself, often in a negative manner. While this cognitive distortion is relevant to depression, it is not mentioned in the question stem and does not directly relate to cognitive processes influenced by depression.

Choice C rationale:

Cognitive distortions are irrational and negative thought patterns that are common in depression. These distortions contribute to the maintenance of depressive symptoms. Examples include all-or-nothing thinking, overgeneralization, and catastrophizing.

Choice D rationale:

Catastrophizing involves magnifying the negative significance of events. While it can contribute to depressive thought patterns, it is not as central to cognitive processes influenced by depression as cognitive distortions are.

Choice E rationale:

Interpersonal relationships are affected by depression and can also contribute to its development. The question does not focus on the effects of depression on relationships, but rather on the factors that can influence or be influenced by depression.

Choice A rationale:

Acetylcholine and gamma-aminobutyric acid (GABA) are not the primary neurotransmitters involved in regulating mood, motivation, reward, cognition, and stress response. Acetylcholine plays a role in memory and muscle control, while GABA is an inhibitory neurotransmitter that helps regulate anxiety and sleep. These neurotransmitters are not as closely associated with the functions mentioned in the question.

Choice B rationale:

Glutamate is a major excitatory neurotransmitter in the central nervous system, and epinephrine (also known as adrenaline) is a hormone that prepares the body for the fight-or-flight response. While both glutamate and epinephrine play important roles in various physiological responses, they are not primarily responsible for regulating mood, motivation, reward, cognition, and stress response as mentioned in the question.

Choice C rationale:

Serotonin, dopamine, and norepinephrine are all key neurotransmitters involved in the regulation of mood, motivation, reward, cognition, and stress response. These neurotransmitters have been extensively studied in the context of mood disorders like Major Depressive Disorder (MDD). Serotonin is often associated with feelings of well-being and happiness, dopamine is linked to pleasure and reward pathways, and norepinephrine is involved in the body's stress response. Imbalances in these neurotransmitters have been implicated in the development of mood disorders.

Choice D rationale:

Endorphins and oxytocin are important neurotransmitters, but they are not as directly related to the regulation of mood, motivation, reward, cognition, and stress response as the neurotransmitters mentioned in choice C. Endorphins are known for their role in pain modulation and feelings of pleasure, while oxytocin is often referred to as the "bonding hormone" and is associated with social connections and childbirth.