A nurse is discussing the process of evidence-based practice with a newly licensed nurse. Which of the following information should the nurse include when discussing a PICOT question?

(A) Encourage the client to increase participation in community social activities: While social activities can be beneficial for mental health, a client at the end of life may not have the physical strength or energy to participate in community social activities. Moreover, due to the compromised immune system in HIV, exposure to large groups could increase the risk of infections.

(B) Prepare the client to begin highly active antiretroviral therapy (HAART): HAART is typically initiated in the early stages of HIV infection to slow the progression of the disease. In a client who has had HIV for 10 years and is at the end of life, the focus would likely be on palliative care and symptom management rather than starting aggressive therapy.

(c) Promote client weight gain of one to two pounds per week: Weight gain might not be a realistic goal for a client at the end of life. Instead, maintaining a balanced diet to prevent malnutrition and managing symptoms like nausea and loss of appetite would be more appropriate.

(D) Provide routine analgesia to minimize episodes of breakthrough pain: This is the most appropriate intervention. Pain management is a critical aspect of end-of-life care. Providing routine analgesia can help ensure the client’s comfort and improve their quality of life. Breakthrough pain can be very distressing for the client, and managing it effectively can significantly enhance their well-being.

Answer: C. Respiratory acidosis

Rationale:

A) Metabolic acidosis: This occurs when there is an excess of acid in the body or a loss of bicarbonate, often due to conditions such as renal failure or severe diarrhea. In chronic bronchitis, the primary issue is related to respiratory function rather than metabolic disturbances.

B) Respiratory alkalosis: This condition results from hyperventilation, leading to excessive loss of carbon dioxide. It is unlikely in a client with chronic bronchitis, who typically experiences difficulty in exhaling fully rather than hyperventilating.

C) Respiratory acidosis: In chronic bronchitis, airflow obstruction and reduced gas exchange can lead to carbon dioxide retention, resulting in respiratory acidosis. Symptoms like dyspnea and increased work of breathing support this imbalance, as the body is unable to adequately expel carbon dioxide.

D) Metabolic alkalosis: This imbalance results from excessive bicarbonate or loss of hydrogen ions, often related to prolonged vomiting or diuretics. It is not characteristic of chronic bronchitis, where the primary concern is respiratory function rather than metabolic processes.