A nurse is caring for a client who is taking azathioprine to treat rheumatoid arthritis. Which of the following laboratory values indicates an adverse effect of this medication?
BUN 15 mg/dL
WBC 3,000/mm
Hct 45%
Platelets 250,000/mm
The Correct Answer is B
Choice A Reason:
BUN 15 mg/dL (blood urea nitrogen) is incorrect. An elevated BUN level can indicate kidney dysfunction or dehydration, but it's not typically associated with azathioprine's adverse effects. Azathioprine is known to affect bone marrow, leading to decreased blood cell counts, rather than directly impacting kidney function.
Choice B Reason:
WBC 3,000/mm³ (low white blood cell count) is correct. Azathioprine is an immunosuppressive medication used to treat various conditions, including rheumatoid arthritis. One of its known adverse effects is bone marrow suppression, which can lead to decreased production of blood cells, including white blood cells (WBCs). A low WBC count (leukopenia) can increase the risk of infections due to compromised immune function, making it an important adverse effect to monitor in individuals taking azathioprine.
Choice C Reason:
Hct 45% (hematocrit) is incorrect. A hematocrit of 45% is within the normal range for both men and women. Azathioprine adverse effects usually manifest as blood cell-related issues (such as leukopenia) rather than directly impacting hematocrit levels.
Choice D Reason:
Platelets 250,000/mm³: Platelets within the range of 150,000 to 400,000/mm³ are considered normal. Azathioprine typically affects white blood cells more prominently than platelet counts.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A Reason:
Rotate the application site every week is correct. Rotating the application site is essential to prevent skin irritation or sensitization. Advising the client to apply the patch to a different area of clean, dry, non-hairy skin each time helps reduce the risk of skin irritation at the application site.
Choice B Reason:
The transdermal patch can cause insomnia is incorrect. Insomnia is a potential side effect of nicotine replacement therapy (NRT) patches, including transdermal nicotine patches, but it's not a universal side effect for everyone using the patch.
Choice C Reason:
Leave the patch in place for 8 hr. each day is incorrect. Transdermal nicotine patches are typically worn for 16–24 hours each day, depending on the specific product instructions. Leaving the patch on for a shorter duration might reduce its effectiveness in supporting smoking cessation.
Choice D Reason:
The transdermal patch releases nicotine rapidly into the bloodstream is incorrect. Transdermal nicotine patches deliver nicotine slowly through the skin into the bloodstream over an extended period rather than providing a rapid release. This gradual release helps reduce cravings and withdrawal symptoms associated with smoking cessation.
Correct Answer is A
Explanation
Choice A Reason:
"I should notify my provider if my stools turn black." This is the appropriate statement. Ferrous gluconate is an iron supplement commonly prescribed to treat or prevent iron deficiency anemia. When taking iron supplements, it's common for stools to become darker or even black in color. This change in stool color is due to the iron and is generally harmless. However, it's essential to inform the healthcare provider about this change because it can also indicate bleeding in the gastrointestinal tract, which requires evaluation.
Choice B Reason:
Taking an antacid with iron supplements can interfere with iron absorption. Antacids may decrease the absorption of iron in the stomach, so it's not recommended to take them together.
Choice C Reason:
While staying upright after taking certain medications can help prevent esophageal irritation or reflux, it's not specifically required with ferrous gluconate.
Choice D Reason:
Taking iron supplements with milk is also not recommended as milk and calcium-containing products can inhibit the absorption of iron. It's generally best to take iron supplements on an empty stomach or with vitamin C to enhance absorption, unless otherwise instructed by the healthcare provider.
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