A nurse is preparing to administer medication to a client who has a prescription for epoetin alfa. Which of the following routes of administration should the nurse plan to use?

Choice A Reason:
Weight gain of 0.7 kg (1.5 lb) in 24 hours is not recommendable. While sudden weight gain can indicate fluid retention, it is not a direct contraindication for administering digoxin. However, it might indicate worsening heart failure, which needs attention, but it doesn't specifically necessitate withholding digoxin.
Choice B Reason:
Urinary output 30 mL/hr is not recommendable. A low urinary output might indicate decreased kidney perfusion or renal issues. While monitoring urinary output is important, it is not a direct reason to withhold digoxin unless it's coupled with severe renal impairment or an acute kidney injury.
For a client receiving digoxin, certain findings would warrant withholding the medication due to potential complications. Among the options provided:
Choice C Reason:
Pulse rate 56/min is the correct recommendation. A low pulse rate (bradycardia), especially below 60 beats per minute, is a reason to withhold digoxin. Digoxin can further decrease the heart rate, potentially leading to excessive bradycardia or heart block. The nurse should hold the medication and consult with the healthcare provider to determine the appropriate action.
Choice D Reason:
BP 160/90 mm Hg is not recommendable. Elevated blood pressure alone is not a direct contraindication for administering digoxin to a patient with heart failure. Digoxin is not primarily used for controlling blood pressure; its use is more focused on managing heart rate and contractility in heart failure patients.

Choice A Reason:
Hct 44% is incorrect. A hematocrit (Hct) level of 44% falls within the normal range for most adults. It represents the proportion of red blood cells in the blood and is not typically concerning unless it significantly deviates from the normal range, indicating anemia or polycythemia.
Choice B Reason:
WBC count 5,000/mm3 is incorrect. A white blood cell (WBC) count of 5,000/mm3 falls within the normal range for adults, reflecting a normal immune response. There's usually no cause for immediate concern unless there are specific clinical symptoms or significant deviations from the normal range.
Choice C Reason:
Potassium 4.2 mEq/L is incorrect. A potassium level of 4.2 mEq/L is within the normal range for serum potassium levels. It's crucial to monitor potassium levels, especially with medications that can affect electrolyte balance, but this value falls within the typical range and may not prompt immediate action unless there are notable fluctuations or clinical symptoms related to potassium imbalance.
While the majority of the laboratory values provided fall within the normal range, the value that the nurse should consider reporting to the provider, particularly when a client is taking amitriptyline, is:
Choice D Reason:
Total bilirubin 1.5 mg/dL is correct. Elevated levels of total bilirubin might indicate potential liver function impairment. Amitriptyline, an antidepressant, can affect liver enzymes in some individuals, causing hepatic changes. Therefore, it's crucial to monitor liver function tests, including total bilirubin, during amitriptyline therapy. An increase in bilirubin levels could signal hepatotoxicity or liver dysfunction related to the medication.